Basic information
- Full name
- aryl hydrocarbon receptor
- Ensembl
- ENSG00000286169.1
- Summary
- The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]
- Annotation
- Transcription factor
Protein product
- ENST00000505113.5 Primary ENSP00000424601.1 (1 phosphosite)
- ENST00000316418.9
- ENST00000512529.5
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | 0.71 | - | 1.5e-10 | - | - | -1.5e-4 | -0.56 | -0.12 | - | 0.72 | - |
protein | - | - | - | - | - | - | - | - | - | - | - |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of AHRR with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
cibersort: B cell naive | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: B cell memory | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: B cell plasma | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD8+ | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ naive | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ memory resting | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ memory activated | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell follicular helper | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell regulatory (Tregs) | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell gamma delta | - | - | - | - | - | - | - | - | - | - | - |
Cis-association
Associations between omics data of AHRR
Trans-association
Associations of the protein abundance of AHRR and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.