Basic information
- Full name
- cell division cycle 14C
- Ensembl
- ENSG00000218305.4
- Summary
- This gene represents a retrogene of cell division cycle 14B (CDC14B), which is located on chromosome 9. The introns in the coding sequence have been processed out relative to the CDC14B locus, but there is an intact open reading frame that is missing only some sequence at the N-terminus, including the nuclear localiztion signal, relative to proteins encoded by the CDC14B gene. There is a difference in the subcellular localization of the protein encoded by this gene, relative to its parental gene product. While the parental gene product displays microtubular localization, GFP chimeras of the protein encoded by this gene localize to the endoplasmic reticulum, indicating a possible new functional role for this gene. [provided by RefSeq, Nov 2017]
- Annotation
- Phosphatase
Protein product
- ENST00000650262.1 Primary ENSP00000497792.1 (0 phosphosite)
- ENST00000428251.2
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | -0.044 | - | 0.12 | - | - | -0.04 | -0.16 | 0.79 | - | -4.4e-3 | - |
protein | - | - | - | - | - | - | - | - | - | - | - |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of CDC14C with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
cibersort: B cell naive | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: B cell memory | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: B cell plasma | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD8+ | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ naive | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ memory resting | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ memory activated | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell follicular helper | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell regulatory (Tregs) | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell gamma delta | - | - | - | - | - | - | - | - | - | - | - |
Cis-association
Associations between omics data of CDC14C
Trans-association
Associations of the protein abundance of CDC14C and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.