Basic information
- Full name
- claudin 17
- Ensembl
- ENSG00000156282.5
- Summary
- This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010]
Protein product
- ENST00000286808.5 Primary ENSP00000286808.3 (0 phosphosite)
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | 0.69 | - | -0.02 | - | - | -1.6e-6 | 1.2e-13 | -0.27 | - | - | - |
protein | - | - | - | - | - | - | - | - | - | - | - |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of CLDN17 with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
cibersort: B cell naive | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: B cell plasma | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD8+ | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ naive | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ memory resting | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell CD4+ memory activated | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell follicular helper | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell regulatory (Tregs) | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: T cell gamma delta | - | - | - | - | - | - | - | - | - | - | - | |
cibersort: NK cell resting | - | - | - | - | - | - | - | - | - | - | - |
Cis-association
Associations between omics data of CLDN17
Trans-association
Associations of the protein abundance of CLDN17 and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.