Basic information
- Full name
- DDB1 and CUL4 associated factor 1
- Ensembl
- ENSG00000145041.15
Protein product
- ENST00000423656.5 Primary ENSP00000393183.2 (14 phosphosites)
- ENST00000504652.5
- ENST00000335891.5
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | -3.7e-18 | - | -4.8e-29 | - | - | -9.3e-5 | -0.95 | -0.025 | - | -0.043 | - |
protein | -3.8e-4 | - | -9.1e-20 | 1.2e-8 | - | -2.1e-10 | 0.24 | 3.0e-5 | -4.7e-4 | -6.4e-4 | 0.2 |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of DCAF1 with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
HALLMARK_MYC_TARGETS_V2 | 3.2e-4 | 0.51 | -0.53 | 0.062 | 7.0e-5 | -0.5 | 8.7e-4 | -0.57 | 0.8 | 0.33 | 0.029 | |
BAP1 mutation | 1.3e-3 | - | 1.3e-3 | - | - | - | - | - | - | - | - | |
KINASE-PSP_CK2A1/CSNK2A1 | 1.4e-3 | 0.044 | 0.75 | 0.27 | 7.5e-3 | 0.66 | 0.028 | 0.49 | -0.11 | 0.55 | 0.088 | |
HALLMARK_SPERMATOGENESIS | 4.4e-3 | 0.14 | 0.39 | -0.88 | 0.028 | 0.059 | 6.5e-3 | -0.078 | -0.27 | 0.072 | 0.3 | |
cibersort: Mast cell activated | 6.3e-3 | 0.8 | -0.84 | 0.62 | -0.94 | 2.1e-3 | 0.51 | 0.089 | -0.69 | 1.7e-3 | -1 | |
xcell: Cancer associated fibroblast | 0.011 | 0.6 | 0.04 | -0.25 | -0.98 | 8.9e-4 | -0.28 | 2.6e-4 | 0.57 | -0.79 | 0.69 | |
Tumor Purity (ABSOLUTE) | 0.011 | 0.049 | -6.0e-4 | 0.069 | 3.2e-4 | -0.36 | 5.4e-3 | -0.4 | 0.19 | -0.62 | 0.027 | |
chromosomal instability | 0.014 | 0.042 | -0.011 | 4.1e-3 | 0.024 | -0.51 | 0.01 | -0.34 | 0.18 | -0.46 | 0.11 | |
PERT-P100-DIA_SEMAGACESTAT | 0.024 | - | - | - | 0.084 | - | 0.14 | - | - | - | - | |
xcell: T cell CD4+ (non-regulatory) | 0.027 | 0.48 | 0.27 | 0.89 | 0.53 | 0.55 | 0.15 | 0.25 | 0.42 | 0.69 | 0.97 |
Cis-association
Associations between omics data of DCAF1
Trans-association
Associations of the protein abundance of DCAF1 and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.