Basic information
- Full name
- nuclear factor I B
- Ensembl
- ENSG00000147862.17
- Annotation
- Transcription factor
Protein product
- ENST00000380959.7 Primary ENSP00000370346.3 (29 phosphosites)
- ENST00000606230.2
- ENST00000543693.5
- ENST00000636735.1
- ENST00000380921.3
- ENST00000622520.1
- ENST00000380924.1
- ENST00000397581.6
- ENST00000646622.1
- ENST00000397575.7
- ENST00000380953.6
- ENST00000397579.6
- ENST00000380934.8
- ENST00000637742.1
- ENST00000636432.1
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | -4e-34 | - | 0.066 | - | - | -5.9e-12 | -2.7e-21 | -7.6e-12 | - | -4.4e-9 | - |
protein | -6.9e-49 | - | 1.9e-7 | -1.8e-14 | - | -3.4e-20 | -1.2e-25 | -3.7e-20 | - | -2.5e-14 | 0.95 |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of NFIB with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
xcell: Hematopoietic stem cell | 9.5e-18 | 0.46 | 6.8e-9 | 0.54 | 0.41 | 4.2e-7 | 1.6e-3 | 1.7e-3 | - | 2.8e-4 | 5.7e-3 | |
xcell: stroma score | 9e-8 | -0.87 | 2.1e-7 | 0.23 | -0.01 | 2.0e-6 | 3.9e-3 | 0.19 | - | 0.096 | 0.078 | |
xcell: Cancer associated fibroblast | 1.4e-7 | 0.11 | 0.85 | 0.17 | -0.54 | 5.2e-8 | 4.1e-3 | 0.14 | - | 0.089 | 0.077 | |
HALLMARK_HEDGEHOG_SIGNALING | 5.0e-5 | 3.2e-3 | 0.11 | -0.57 | 0.39 | 3.6e-3 | 0.14 | 0.23 | - | 0.078 | -0.99 | |
HALLMARK_WNT_BETA_CATENIN_SIGNALING | 3.8e-4 | 2.7e-6 | 2.8e-4 | 0.68 | 0.27 | 0.29 | -0.75 | -0.21 | - | -0.26 | 0.014 | |
xcell: T cell CD4+ central memory | 8.8e-4 | -0.68 | 0.035 | 0.64 | 0.041 | 0.93 | 0.77 | 0.06 | - | 0.22 | 0.021 | |
cibersort: T cell CD4+ memory resting | 9.3e-4 | 0.71 | 0.11 | -0.16 | 0.42 | 0.33 | 0.13 | 0.07 | - | 1.8e-3 | 0.24 | |
HALLMARK_PANCREAS_BETA_CELLS | 1.6e-3 | -0.48 | 2.1e-3 | -0.14 | 1.9e-3 | 0.049 | 0.29 | 0.3 | - | 0.039 | -0.52 | |
PERT-P100-PRM_VORINOSTAT | 1.9e-3 | - | - | - | 1.9e-3 | - | - | - | - | - | - | |
KINASE-PSP_JNK1/MAPK8 | 2.3e-3 | - | - | - | 7.7e-4 | - | - | - | - | - | 0.34 |
Cis-association
Associations between omics data of NFIB
Trans-association
Associations of the protein abundance of NFIB and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.