Basic information
- Full name
- PWWP domain containing 2A
- Ensembl
- ENSG00000170234.13
Protein product
- ENST00000307063.9 Primary ENSP00000305151.7 (10 phosphosites)
- ENST00000456329.7
- ENST00000523662.1
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | 7.7e-6 | - | 1.1e-27 | - | - | -1.7e-3 | -1.4e-7 | 5.4e-10 | - | 0.19 | - |
protein | 3.1e-4 | - | 1.9e-13 | -0.041 | - | 0.73 | 0.46 | 6.6e-12 | 0.091 | -0.021 | -0.014 |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of PWWP2A with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
xcell: T cell CD4+ Th1 | 3.8e-7 | 0.02 | 0.24 | 0.22 | 0.43 | 0.17 | 0.005 | 0.025 | 0.39 | 0.005 | 0.65 | |
chromosomal instability | 7.2e-6 | 0.18 | 0.023 | -0.32 | 0.028 | 0.62 | 0.15 | 2.7e-4 | 0.25 | 0.14 | 0.24 | |
Tumor Purity (WGS) | 6.3e-5 | - | 0.45 | - | 0.27 | -0.96 | 0.068 | 1.6e-6 | - | 0.059 | 0.79 | |
Tumor Purity (ABSOLUTE) | 1.1e-3 | 0.36 | 0.43 | -0.74 | 0.069 | -0.58 | 0.2 | 5.0e-4 | 0.045 | 0.28 | -0.86 | |
HALLMARK_DNA_REPAIR | 1.1e-3 | 0.014 | 0.23 | -0.61 | 0.057 | 4.7e-3 | 0.13 | 0.91 | 0.92 | 0.31 | -0.74 | |
HALLMARK_E2F_TARGETS | 1.6e-3 | 0.6 | 0.38 | 0.69 | 0.033 | 0.016 | 0.016 | -0.59 | 0.67 | 0.16 | -0.96 | |
HALLMARK_G2M_CHECKPOINT | 0.002 | 0.7 | 0.61 | 0.7 | 0.025 | 0.073 | 0.045 | -0.78 | 0.37 | 0.24 | 0.5 | |
Clinical: Stage | 3.4e-3 | -0.52 | 0.24 | 0.95 | - | 0.29 | 0.043 | 0.18 | 0.22 | 0.21 | 0.2 | |
KINASE-PSP_CK2A1/CSNK2A1 | 0.004 | -0.49 | 0.89 | 0.031 | 0.041 | 0.083 | 0.12 | 0.27 | -0.4 | 0.19 | 0.56 | |
PBRM1 mutation | 4.2e-3 | - | 4.2e-3 | - | - | - | - | - | - | - | - |
Cis-association
Associations between omics data of PWWP2A
Trans-association
Associations of the protein abundance of PWWP2A and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.