Basic information
- Full name
- RAB interacting factor
- Ensembl
- ENSG00000183155.5
- Summary
- This gene encodes a member of the SCE4/YPT1/RAB family of small GTP-binding proteins that are involved in the regulation of intracellular vesicular transport. This protein stimulates GTP-GDP exchange in SEC4, and to a lesser extent in YPT1 and RAB3A, and may play a general role in vesicular transport. [provided by RefSeq, Oct 2011]
Protein product
- ENST00000367262.4 Primary ENSP00000356231.3 (0 phosphosite)
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | 6.6e-15 | - | -4.7e-6 | - | - | -0.16 | 2.1e-16 | 2.5e-28 | - | 3.1e-5 | - |
protein | 1.7e-18 | - | 8.5e-11 | 0.53 | - | 0.47 | 2.7e-3 | 1.4e-15 | 0.25 | 4.9e-5 | 0.43 |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of RABIF with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
KINASE-PSP_AMPKA1/PRKAA1 | 1.2e-4 | - | - | - | -0.73 | - | - | - | - | 1.3e-7 | 0.082 | |
KINASE-PSP_CDK5 | 1.2e-3 | - | - | - | 8.7e-4 | -0.85 | -0.92 | - | - | 0.039 | 0.03 | |
BAP1 mutation | 2.5e-3 | - | 2.5e-3 | - | - | - | - | - | - | - | - | |
PROGENy: p53 | 3.8e-3 | 0.28 | -0.11 | 0.31 | -0.41 | 6.9e-3 | 0.45 | 0.009 | 0.42 | 6.4e-3 | -0.9 | |
SBS20 (POLD1 mutation and defective DNA mismatch repair) | 8.1e-3 | - | - | 8.1e-3 | - | - | - | - | - | - | - | |
xcell: T cell CD8+ | 8.4e-3 | -0.18 | 0.76 | 0.28 | 0.67 | 4.8e-3 | 0.013 | -0.65 | 0.53 | 0.24 | 0.22 | |
EGFR mutation | 0.01 | - | - | - | 0.36 | - | - | 6.6e-3 | - | - | - | |
PROGENy: JAK-STAT | 0.011 | -0.38 | 0.52 | 0.12 | 0.87 | 0.037 | 0.033 | 0.06 | 0.04 | -3.2e-3 | 0.18 | |
xcell: T cell CD8+ effector memory | 0.011 | -0.4 | 0.36 | 4.7e-3 | 0.35 | 0.1 | 7.5e-3 | -0.9 | -0.3 | 0.84 | 0.4 | |
HALLMARK_PEROXISOME | 0.016 | 0.1 | 3.1e-3 | -0.2 | 0.6 | -0.51 | -0.87 | 3.9e-4 | 0.4 | 0.97 | 0.86 |
Cis-association
Associations between omics data of RABIF
Trans-association
Associations of the protein abundance of RABIF and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.