Basic information
- Full name
- unc-50 inner nuclear membrane RNA binding protein
- Ensembl
- ENSG00000115446.11
- Annotation
- Essential genes
Protein product
- ENST00000357765.6 Primary ENSP00000350409.2 (1 phosphosite)
- ENST00000409975.5
- ENST00000409347.5
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | 0.59 | - | 0.026 | - | - | -0.063 | -0.35 | 0.061 | - | -0.93 | - |
protein | - | - | - | - | - | - | - | - | - | - | - |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of UNC50 with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
PROGENy: NFkB | 7.2e-3 | - | - | - | - | - | - | - | - | - | 7.2e-3 | |
PROGENy: TNFa | 0.01 | - | - | - | - | - | - | - | - | - | 0.01 | |
HALLMARK_INFLAMMATORY_RESPONSE | 0.013 | - | - | - | - | - | - | - | - | - | 0.013 | |
xcell: Monocyte | 0.018 | - | - | - | - | - | - | - | - | - | 0.018 | |
HALLMARK_TNFA_SIGNALING_VIA_NFKB | 0.019 | - | - | - | - | - | - | - | - | - | 0.019 | |
HALLMARK_IL6_JAK_STAT3_SIGNALING | 0.024 | - | - | - | - | - | - | - | - | - | 0.024 | |
PERT-PSP_PHORBOL_ESTER | 0.028 | - | - | - | - | - | - | - | - | - | 0.028 | |
KINASE-PSP_P38A/MAPK14 | 0.034 | - | - | - | - | - | - | - | - | - | 0.034 | |
cibersort: Neutrophil | 0.042 | - | - | - | - | - | - | - | - | - | 0.042 | |
xcell: Myeloid dendritic cell | 0.05 | - | - | - | - | - | - | - | - | - | 0.05 |
Cis-association
Associations between omics data of UNC50
Trans-association
Associations of the protein abundance of UNC50 and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.