Basic information
- Full name
- upregulator of cell proliferation
- Ensembl
- ENSG00000106608.16
- Summary
- URG4 is upregulated in the presence of hepatitis B virus (HBV)-encoded X antigen (HBxAg) and may contribute to the development of hepatocellular carcinoma by promoting hepatocellular growth and survival (Tufan et al., 2002 [PubMed 12082552]).[supplied by OMIM, Mar 2008]
Protein product
- ENST00000453200.5 Primary ENSP00000396918.1 (1 phosphosite)
- ENST00000402306.7
- ENST00000336086.10
- ENST00000443736.5
- ENST00000446958.1
Phosphosites on the primary protein product
Tumor and normal comparison
Signed p-values | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Data type | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
RNA | -0.12 | - | -1.3e-19 | - | - | -0.95 | 0.59 | 3.6e-9 | - | -0.45 | - |
protein | 3.2e-14 | - | -4.6e-4 | 0.011 | - | 1.1e-5 | 8.2e-12 | 1.7e-19 | -0.45 | 0.81 | 6.7e-3 |
mRNA expression at gene level
Protein expression
Phenotype and mutation association
Manhattan plot summarizing associations of phenotypes and mutations across all cohorts and omics data types
Associations of the protein abundance of URGCP with phenotypes and mutations
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
chromosomal instability | 1.7e-6 | 0.11 | 0.008 | 0.18 | 0.39 | 0.69 | 0.8 | 1.4e-3 | 0.24 | 0.12 | 0.036 | |
PROGENy: PI3K | 2.4e-6 | 0.05 | -0.75 | 0.062 | 2.3e-3 | 1.0e-4 | 0.066 | -0.91 | 0.073 | -0.77 | 0.21 | |
PROGENy: VEGF | 1.6e-5 | -0.72 | 0.78 | -0.35 | 0.002 | 5.0e-5 | 0.051 | 7.1e-6 | 0.84 | 0.17 | -0.61 | |
KINASE-PSP_CDK1 | 6.3e-5 | 0.5 | -0.71 | 0.5 | 0.032 | 0.014 | 0.54 | 0.063 | 0.027 | 0.01 | -0.85 | |
HALLMARK_GLYCOLYSIS | 2.4e-4 | 0.26 | 2.1e-6 | -0.18 | 0.1 | 0.056 | -0.34 | 0.079 | 0.15 | 0.35 | 0.73 | |
PERT-PSP_NOCODAZOLE | 1.4e-3 | 0.72 | 0.33 | 0.51 | 0.29 | 0.18 | 0.33 | 0.016 | 0.56 | 0.052 | -0.87 | |
PERT-P100-DIA_SEMAGACESTAT | 2.5e-3 | - | - | - | 0.061 | - | 0.016 | - | - | - | - | |
PATH-NP_TSLP_PATHWAY | 2.7e-3 | 0.49 | 0.32 | 0.43 | 0.83 | 0.09 | 0.28 | 0.96 | 0.14 | 0.083 | 0.44 | |
HALLMARK_DNA_REPAIR | 4.2e-3 | -0.4 | 0.42 | 0.082 | 5.9e-3 | 0.02 | -0.67 | 0.16 | -0.46 | 0.037 | -0.96 | |
PERT-P100-PRM_VORINOSTAT | 6.6e-3 | - | - | - | 6.6e-3 | - | - | - | - | - | - |
Cis-association
Associations between omics data of URGCP
Trans-association
Associations of the protein abundance of URGCP and the protein abundance of other genes
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | |
No matching records found |
Gene set enrichment analysis
Submit genes and the common logarithm of the p-values of their association with to WebGestalt.