Protein: ENSP00000000233

ARF5:: ADP ribosylation factor 5

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S137	MPNAMPVSELTDKLG	5	77	16	-	4	4	-	-	9	-	-	-	-	-	8	8	-	-	-	-	23	5

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S137	MPNAMPVSELTDKLG	-	-	-	-	-	-	-	-	-	-	-

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
HALLMARK_KRAS_SIGNALING_UP	S137	1.4e-3	0.036	-	-	-	-	-	-	-	-	0.015
HALLMARK_APICAL_JUNCTION	S137	2.8e-3	0.052	-	-	-	-	-	-	-	-	0.022
HALLMARK_HEDGEHOG_SIGNALING	S137	3.5e-3	0.037	-	-	-	-	-	-	-	-	0.04
ESTIMATE: StromalScore	S137	4.7e-3	0.07	-	-	-	-	-	-	-	-	0.029
HALLMARK_UV_RESPONSE_DN	S137	4.8e-3	0.11	-	-	-	-	-	-	-	-	0.016
Clinical: Age	S137	0.005	0.17	-	-	-	-	-	-	-	-	8.9e-3
HALLMARK_NOTCH_SIGNALING	S137	7.2e-3	0.1	-	-	-	-	-	-	-	-	0.03
ESTIMATE: ESTIMATEScore	S137	8.1e-3	0.17	-	-	-	-	-	-	-	-	0.018
xcell: Endothelial cell	S137	8.5e-3	0.024	-	-	-	-	-	-	-	-	0.14
SBS7a (UVR)	S137	0.01	0.049	-	-	-	-	-	-	-	-	0.098

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* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
MAP3K3	S137	5.1e-4	9.8e-3	-	-	-	-	-	-	-	-	0.02
TESK2	S137	4.4e-3	4.4e-3	-	-	-	-	-	-	-	-	-
PRKAA2	S137	4.6e-3	0.17	-	-	-	-	-	-	-	-	8.1e-3
GRK3	S137	4.7e-3	0.045	-	-	-	-	-	-	-	-	0.047
SIK2	S137	5.1e-3	0.017	-	-	-	-	-	-	-	-	0.12
TNK2	S137	5.5e-3	0.061	-	-	-	-	-	-	-	-	0.04
JAK2	S137	5.8e-3	0.08	-	-	-	-	-	-	-	-	0.031
MAPK3	S137	0.008	0.15	-	-	-	-	-	-	-	-	0.02
CAMK1	S137	9.9e-3	0.01	-	-	-	-	-	-	-	-	0.28
MKNK1	S137	0.01	0.022	-	-	-	-	-	-	-	-	0.18

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* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
DUSP11	S137	-0.013	-0.18	-	-	-	-	-	-	-	-	-0.028
ILKAP	S137	-0.016	-0.03	-	-	-	-	-	-	-	-	-0.22
SSU72	S137	-0.031	-0.017	-	-	-	-	-	-	-	-	-0.51
BPNT1	S137	-0.033	-0.072	-	-	-	-	-	-	-	-	-0.22
PGAM5	S137	-0.039	-0.39	-	-	-	-	-	-	-	-	-0.04
PPM1D	S137	-0.051	-0.051	-	-	-	-	-	-	-	-	-
CTDSPL2	S137	-0.055	-0.12	-	-	-	-	-	-	-	-	-0.25
NT5DC1	S137	-0.094	-0.51	-	-	-	-	-	-	-	-	-0.086
PGP	S137	-0.099	-0.51	-	-	-	-	-	-	-	-	-0.093
EYA2	S137	-0.14	-	-	-	-	-	-	-	-	-	-0.14

Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000000233Gene: ARF5

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000000233
Gene: ARF5