Protein: ENSP00000005587
Gene: SKAP2

LinkedOmicsKB © 2022-2023 Zhang Lab

SKAP2:
src kinase associated phosphoprotein 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S5___MPNPSSTSSPYP352--44------541817------
S6__MPNPSSTSSPYPL1054016-87676846-27153027222067175324242
T7_MPNPSSTSSPYPLP7156--774553---5454--1862711
S8MPNPSSTSSPYPLPE712226-888109-631412108------
S9PNPSSTSSPYPLPEE27218---------2826--------
S47KAKEKRESLIKKIKD36218-----------54--2411--
Y75DAEDGEEYDDPFAGP19------9-------------
T85PFAGPPDTISLASER633842-5736----613914132625--187--
S87AGPPDTISLASERYD956026-1716131499-18859553633--74334415
S90PDTISLASERYDKDD8202--178--9-161119185451836018
Showing 1 to 10 of 18 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S5___MPNPSSTSSPYP-----------
S6__MPNPSSTSSPYPL-0.006--1.8e-3--0.035-1.2e-7-0.032-3.1e-49.5e-4-
T7_MPNPSSTSSPYPLP-0.17----------0.17
S8MPNPSSTSSPYPLPE-----------
S9PNPSSTSSPYPLPEE-0.24------0.24----
S47KAKEKRESLIKKIKD4.8e-5--------4.8e-5-
Y75DAEDGEEYDDPFAGP-----------
T85PFAGPPDTISLASER6.6e-5-9.6e-9--9.0e-5--6.1e-3---
S87AGPPDTISLASERYD-7.2e-6------3.6e-12-1.8e-3--0.250.025
S90PDTISLASERYDKDD0.02---------0.02
Showing 1 to 10 of 18 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationCCRCCS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationCOADS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationGBMS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationHNSCCS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationLSCCS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationLUADS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationOVS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationPDACS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylationUCECS5S6T7S8S9S47Y75T85S87S90S101S131Y151T176Y197S203S283S286proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.