PSD: pleckstrin and Sec7 domain containing
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S17 SEGDCAIS PPRCPRR 1 99 - - - - - - 99 - - - - - - - - - - - - - S34 PEGPVPQS PPASMYG 1 89 - - - - - - 89 - - - - - - - - - - - - - T68 GRVTAPCT PLRGPPS 1 9 - - - - - - 9 - - - - - - - - - - - - - S75 TPLRGPPS PRVAPSP 2 115 25 - - - - - 90 - - - - - - - - - - - - - S81 PSPRVAPS PWAPSSP 1 9 - - - - - - 9 - - - - - - - - - - - - - S86 APSPWAPS SPTGQPP 1 9 - - - - - - 9 - - - - - - - - - - - - - S87 PSPWAPSS PTGQPPP 1 71 - - - - - - 71 - - - - - - - - - - - - - T89 PWAPSSPT GQPPPGA 1 9 - - - - - - 9 - - - - - - - - - - - - - S126 APGGLSRS WDLGGVS 1 89 - - - - - - 89 - - - - - - - - - - - - - S133 SWDLGGVS PPRPTPA 1 99 - - - - - - 99 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S17 SEGDCAIS PPRCPRR - - - - - - - - - - - S34 PEGPVPQS PPASMYG - - - - - - - - - - - T68 GRVTAPCT PLRGPPS - - - - - - - - - - - S75 TPLRGPPS PRVAPSP - - - - - - - - - - - S81 PSPRVAPS PWAPSSP - - - - - - - - - - - S86 APSPWAPS SPTGQPP - - - - - - - - - - - S87 PSPWAPSS PTGQPPP - - - - - - - - - - - T89 PWAPSSPT GQPPPGA - - - - - - - - - - - S126 APGGLSRS WDLGGVS - - - - - - - - - - - S133 SWDLGGVS PPRPTPA - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S17
S34
T68
S75
S81
S86
S87
T89
S126
S133
T155
S156
S191
S224
S263
S273
S284
S344
S347
S393
S501
S543
T544
S720
S722
S736
S739
S741
S743
S744
S785
S990
S992
S993
S1010
S1011
S1019
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation CCRCC S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation COAD S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation GBM S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation HNSCC S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation LSCC S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation LUAD S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation OV S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation PDAC S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation UCEC S17 S34 T68 S75 S81 S86 S87 T89 S126 S133 T155 S156 S191 S224 S263 S273 S284 S344 S347 S393 S501 S543 T544 S720 S722 S736 S739 S741 S743 S744 S785 S990 S992 S993 S1010 S1011 S1019 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S17
S34
T68
S75
S81
S86
S87
T89
S126
S133
T155
S156
S191
S224
S263
S273
S284
S344
S347
S393
S501
S543
T544
S720
S722
S736
S739
S741
S743
S744
S785
S990
S992
S993
S1010
S1011
S1019
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S17
S34
T68
S75
S81
S86
S87
T89
S126
S133
T155
S156
S191
S224
S263
S273
S284
S344
S347
S393
S501
S543
T544
S720
S722
S736
S739
S741
S743
S744
S785
S990
S992
S993
S1010
S1011
S1019
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.