CDC27: cell division cycle 27
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3t1n chain C
3t1n chain D
4rg6 chain A
4rg6 chain B
4rg7 chain A
4rg7 chain B
4rg9 chain A
4rg9 chain B
4ui9 chain F
4ui9 chain H
5a31 chain F
5a31 chain H
5g04 chain F
5g04 chain H
5g05 chain F
5g05 chain H
5khr chain F
5khr chain H
5khu chain F
5khu chain H
5l9t chain F
5l9t chain H
5l9u chain F
5l9u chain H
5lcw chain F
5lcw chain H
6q6g chain J
6q6g chain P
6q6h chain J
6q6h chain P
6tlj chain F
6tlj chain H
6tm5 chain F
6tm5 chain H
6tnt chain F
6tnt chain H
7qe7 chain J
7qe7 chain P
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T205 PETVLTET PQDTIEL 1 48 - - - - - - - - - - - - - - - - - - 41 7 S220 NRLNLESS NSKYSLN 8 557 6 - - - - - 72 - 15 10 75 69 49 45 55 12 51 19 63 16 S237 SSVSYIDS AVISPDT 2 45 - - - - - - - - - - 19 18 4 4 - - - - - - S241 YIDSAVIS PDTVPLG 2 50 - - - - - - - - 28 14 - - 4 4 - - - - - - T244 SAVISPDT VPLGTGT 1 36 - - - - - - - - 24 12 - - - - - - - - - - S336 TKSVFSQS GNSREVT 5 131 - - 8 - - - - - - - - - 5 4 6 2 51 24 28 3 T356 TQSSGPQT STTPQVL 5 71 - - 5 4 - - 9 - 11 6 7 8 - - - - - - 19 2 S357 QSSGPQTS TTPQVLS 2 13 - - 8 - - - - - - - - - - - - - 3 2 - - T358 SSGPQTST TPQVLSP 3 25 - - 4 4 - - - - 5 3 - - 5 4 - - - - - - T359 SGPQTSTT PQVLSPT 5 57 15 - 4 4 - - - - - - 5 5 9 8 - - - - 7 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T205 PETVLTET PQDTIEL - - - - - - - - - - - S220 NRLNLESS NSKYSLN -4.9e-24 - - - - - -3.6e-18 -3e-14 -8.7e-3 -0.93 -3.1e-4 S237 SSVSYIDS AVISPDT - - - - - - - - - - - S241 YIDSAVIS PDTVPLG -1.1e-3 - - - - -1.1e-3 - - - - - T244 SAVISPDT VPLGTGT -0.026 - - - - -0.026 - - - - - S336 TKSVFSQS GNSREVT -1.2e-3 - - - - - - - - -1.2e-3 - T356 TQSSGPQT STTPQVL - - - - - - - - - - - S357 QSSGPQTS TTPQVLS - - - - - - - - - - - T358 SSGPQTST TPQVLSP - - - - - - - - - - - T359 SGPQTSTT PQVLSPT - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T205
S220
S237
S241
T244
S336
T356
S357
T358
T359
S364
T368
S369
S379
T383
S387
S426
S435
T446
S821
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation CCRCC T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation COAD T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation GBM T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation HNSCC T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation LSCC T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation LUAD T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation OV T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation PDAC T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation UCEC T205 S220 S237 S241 T244 S336 T356 S357 T358 T359 S364 T368 S369 S379 T383 S387 S426 S435 T446 S821 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T205
S220
S237
S241
T244
S336
T356
S357
T358
T359
S364
T368
S369
S379
T383
S387
S426
S435
T446
S821
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T205
S220
S237
S241
T244
S336
T356
S357
T358
T359
S364
T368
S369
S379
T383
S387
S426
S435
T446
S821
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.