Protein: ENSP00000162330
Gene: BCAR1

LinkedOmicsKB © 2022-2023 Zhang Lab

BCAR1:
BCAR1 scaffold protein, Cas family member

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y128SKAQQGLYQVPGPSP6174--44--9-1692525----18104113
S134LYQVPGPSPQFQSPP5829-8-----731513------252
S139GPSPQFQSPPAKQTS6207--33--27-39224440----114122
S202PPSMDTRSWEGTKPP82438-44--9-181053471311--3617112
Y234AQPEQDEYDIPRHLL1084287-2927181845-18910395867727772287818
Y249APGPQDIYDVPPVRG1055017-484411718-19105047686046122285013
Y267SQYGQEVYDTPPMAV615923---5418---191954----539
T326GPLLREETYDVPPAF199-------------------
Y327PLLREETYDVPPAFA7238--1816--18-10638361512153--3516
S355LAAPPPDSPPAEDVY105817-5340726942-563310954816223789
Showing 1 to 10 of 26 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y128SKAQQGLYQVPGPSP-8.4e-5------2e-7----0.72
S134LYQVPGPSPQFQSPP-----------
S139GPSPQFQSPPAKQTS-2.6e-3-----0.013-0.075----
S202PPSMDTRSWEGTKPP4.3e-4------0.14--9.9e-11-
Y234AQPEQDEYDIPRHLL-2.2e-11--0.053----2.3e-14-4.1e-5--2.3e-30.08
Y249APGPQDIYDVPPVRG-2.6e-7--0.47----5.0e-6-1.9e-7-0.025-0.22
Y267SQYGQEVYDTPPMAV-----------
T326GPLLREETYDVPPAF-----------
Y327PLLREETYDVPPAFA-6e-10------9.3e-14----0.19
S355LAAPPPDSPPAEDVY-0.7--1.9e-40.52--0.12---1.1e-4-
Showing 1 to 10 of 26 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationCCRCCY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationCOADY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationGBMY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationHNSCCY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationLSCCY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationLUADY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationOVY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationPDACY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylationUCECY128S134S139S202Y234Y249Y267T326Y327S355Y362Y387Y410S428S430S431S434S438S440S533S639S648Y653S656Y664S694proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.