CDK13: cyclin dependent kinase 13
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5efq chain A
5efq chain C
7nxj chain A
7nxj chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S3 _____MPS SSDTALG 1 9 - - - - - - - - - - - - - - 7 2 - - - - S4 ____MPSS SDTALGG 2 18 9 - - - - - - - - - - - 5 4 - - - - - - S5 ___MPSSS DTALGGG 3 46 18 - - - - - - - - - - - 5 4 - - - - 17 2 T7 _MPSSSDT ALGGGGG 1 7 7 - - - - - - - - - - - - - - - - - - - S194 TQRRGEGS ERRPRRD 1 5 - - - - - - - - - - - - - - - - 4 1 - - S236 SKSRSRHS HSGEERA 2 30 21 - - - - - 9 - - - - - - - - - - - - - S238 SRSRHSHS GEERAEV 2 30 21 - - - - - 9 - - - - - - - - - - - - - S260 SSGGRRKS ASATSSS 7 390 - - - - 14 13 90 - - - 60 54 40 35 16 1 3 2 44 18 S286 HRSRTKSS KEPPSAY 2 48 9 - - - - - - - - - 20 19 - - - - - - - - S315 KAYRRRRS LSPLGGR 10 1078 55 - 30 28 80 72 99 - 82 48 93 87 77 68 8 1 100 42 90 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S3 _____MPS SSDTALG - - - - - - - - - - - S4 ____MPSS SDTALGG - - - - - - - - - - - S5 ___MPSSS DTALGGG - - - - - - - - - - - T7 _MPSSSDT ALGGGGG - - - - - - - - - - - S194 TQRRGEGS ERRPRRD - - - - - - - - - - - S236 SKSRSRHS HSGEERA - - - - - - - - - - - S238 SRSRHSHS GEERAEV - - - - - - - - - - - S260 SSGGRRKS ASATSSS -1.9e-5 - - - - - -0.023 0.059 - - -2.3e-12 S286 HRSRTKSS KEPPSAY -2.3e-4 - - - - - -2.3e-4 - - - - S315 KAYRRRRS LSPLGGR 5.8e-12 - 0.65 0.066 - 9.0e-4 0.013 9.3e-14 - 1.1e-3 -0.55
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S3
S4
S5
T7
S194
S236
S238
S260
S286
S315
S317
S325
S340
S342
S348
S349
S358
S360
S383
S385
S391
S395
S397
Y399
S400
S409
S411
S413
S420
S433
S436
S437
S439
S490
T492
T494
S525
S528
T588
S662
S664
S864
S867
Y870
T871
S1048
S1054
T1056
T1058
T1147
T1226
T1246
T1482
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation CCRCC S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation COAD S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation GBM S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation HNSCC S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation LSCC S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation LUAD S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation OV S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation PDAC S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation UCEC S3 S4 S5 T7 S194 S236 S238 S260 S286 S315 S317 S325 S340 S342 S348 S349 S358 S360 S383 S385 S391 S395 S397 Y399 S400 S409 S411 S413 S420 S433 S436 S437 S439 S490 T492 T494 S525 S528 T588 S662 S664 S864 S867 Y870 T871 S1048 S1054 T1056 T1058 T1147 T1226 T1246 T1482 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S3
S4
S5
T7
S194
S236
S238
S260
S286
S315
S317
S325
S340
S342
S348
S349
S358
S360
S383
S385
S391
S395
S397
Y399
S400
S409
S411
S413
S420
S433
S436
S437
S439
S490
T492
T494
S525
S528
T588
S662
S664
S864
S867
Y870
T871
S1048
S1054
T1056
T1058
T1147
T1226
T1246
T1482
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S3
S4
S5
T7
S194
S236
S238
S260
S286
S315
S317
S325
S340
S342
S348
S349
S358
S360
S383
S385
S391
S395
S397
Y399
S400
S409
S411
S413
S420
S433
S436
S437
S439
S490
T492
T494
S525
S528
T588
S662
S664
S864
S867
Y870
T871
S1048
S1054
T1056
T1058
T1147
T1226
T1246
T1482
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.