ITGB4: integrin subunit beta 4
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1qg3 chain A
1qg3 chain B
2yrz chain A
3f7p chain C
3f7p chain D
3f7p chain E
3f7q chain A
3f7q chain B
3f7r chain A
3fq4 chain A
3fq4 chain B
3fso chain A
3fso chain B
3h6a chain A
3h6a chain B
4q58 chain C
4q58 chain D
4wtw chain A
4wtw chain B
4wtx chain A
6gvk chain A
6gvl chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y50 RVDKDCAY CTDEMFR 1 9 - - - - - - - - - - - - 5 4 - - - - - - T52 DKDCAYCT DEMFRDR 1 9 - - - - - - - - - - - - 5 4 - - - - - - S397 FQKTRTGS FHIRRGE 3 67 - - - - - - - - 25 12 9 9 - - - - 8 4 - - S771 LRENLMAS DHLDTPM 2 37 - - - - - - 9 - 17 11 - - - - - - - - - - S809 GFATHAAS INPTELV 10 948 29 - 90 68 62 63 99 - 108 62 94 85 30 30 11 5 75 31 6 - T971 AIDVPAGT ATLGRRL 8 149 7 - 9 8 30 24 9 - 11 6 10 9 4 4 - - 13 5 - - S1000 SFEQPEFS VSRGDQV 6 248 - - - - 31 32 9 - 36 18 48 44 - - 11 3 - - 14 2 S1002 EQPEFSVS RGDQVAR 2 15 - - - - - - - - 6 3 - - - - - - - - 6 - S1069 LELQEVDS LLRGRQV 10 1057 48 - 86 64 92 96 72 - 108 62 83 74 35 33 18 6 98 41 25 16 S1084 RRFHVQLS NPKFGAH 9 468 - - 4 4 12 14 53 - 49 29 88 79 8 8 15 3 48 18 24 12
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y50 RVDKDCAY CTDEMFR - - - - - - - - - - - T52 DKDCAYCT DEMFRDR - - - - - - - - - - - S397 FQKTRTGS FHIRRGE 6.9e-3 - - - - 6.9e-3 - - - - - S771 LRENLMAS DHLDTPM - - - - - - - - - - - S809 GFATHAAS INPTELV 4.6e-19 - 3e-15 -0.38 - 0.014 1.9e-8 0.02 - 8.8e-6 - T971 AIDVPAGT ATLGRRL -0.016 - - -0.016 - - - - - - - S1000 SFEQPEFS VSRGDQV 0.97 - - -0.004 - -0.046 8e-7 - - - - S1002 EQPEFSVS RGDQVAR - - - - - - - - - - - S1069 LELQEVDS LLRGRQV 1e-34 - 3e-16 0.025 - 3.3e-14 2.7e-18 -0.82 - 6.7e-17 -0.02 S1084 RRFHVQLS NPKFGAH 3.8e-20 - - - - 2.4e-6 1.3e-24 - - 0.013 0.34
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y50
T52
S397
S771
S809
T971
S1000
S1002
S1069
S1084
S1111
T1113
S1114
S1169
S1180
T1184
Y1207
S1208
S1209
S1325
S1339
Y1343
S1356
S1360
S1364
S1401
S1408
T1434
S1454
T1455
S1457
Y1469
T1471
S1474
S1483
S1485
S1486
T1487
S1494
T1496
S1498
S1501
S1503
T1505
S1515
S1517
S1518
S1521
T1530
S1537
S1547
S1584
S1595
S1604
T1688
S1696
S1747
S1791
T1797
T1822
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation CCRCC Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation COAD Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation GBM Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation HNSCC Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation LSCC Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation LUAD Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation OV Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation PDAC Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation UCEC Y50 T52 S397 S771 S809 T971 S1000 S1002 S1069 S1084 S1111 T1113 S1114 S1169 S1180 T1184 Y1207 S1208 S1209 S1325 S1339 Y1343 S1356 S1360 S1364 S1401 S1408 T1434 S1454 T1455 S1457 Y1469 T1471 S1474 S1483 S1485 S1486 T1487 S1494 T1496 S1498 S1501 S1503 T1505 S1515 S1517 S1518 S1521 T1530 S1537 S1547 S1584 S1595 S1604 T1688 S1696 S1747 S1791 T1797 T1822 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y50
T52
S397
S771
S809
T971
S1000
S1002
S1069
S1084
S1111
T1113
S1114
S1169
S1180
T1184
Y1207
S1208
S1209
S1325
S1339
Y1343
S1356
S1360
S1364
S1401
S1408
T1434
S1454
T1455
S1457
Y1469
T1471
S1474
S1483
S1485
S1486
T1487
S1494
T1496
S1498
S1501
S1503
T1505
S1515
S1517
S1518
S1521
T1530
S1537
S1547
S1584
S1595
S1604
T1688
S1696
S1747
S1791
T1797
T1822
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
Y50
T52
S397
S771
S809
T971
S1000
S1002
S1069
S1084
S1111
T1113
S1114
S1169
S1180
T1184
Y1207
S1208
S1209
S1325
S1339
Y1343
S1356
S1360
S1364
S1401
S1408
T1434
S1454
T1455
S1457
Y1469
T1471
S1474
S1483
S1485
S1486
T1487
S1494
T1496
S1498
S1501
S1503
T1505
S1515
S1517
S1518
S1521
T1530
S1537
S1547
S1584
S1595
S1604
T1688
S1696
S1747
S1791
T1797
T1822
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.