ESF1: ESF1 nucleolar pre-rRNA processing protein homolog
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S75 LKRFYDLS DSDSNLS 8 132 22 - 4 4 4 5 18 - 16 11 - - - - 30 6 5 1 6 - S77 RFYDLSDS DSNLSGE 8 124 6 - 8 8 4 5 - - 16 11 9 9 - - 7 1 13 5 19 3 S79 YDLSDSDS NLSGEDS 6 104 19 - 4 4 - - - - 16 11 5 5 - - - - 13 5 19 3 S82 SDSDSNLS GEDSKAL 2 45 - - 4 4 - - - - - - 20 17 - - - - - - - - S134 NKTDLDNS IGIKKMK 6 220 42 - 20 10 - - 9 - - - 50 47 16 16 - - - - 10 - S153 FKIDSNIS PKKDSKE 10 1523 122 - 99 76 97 100 99 - 108 62 108 97 106 96 76 17 103 44 95 18 S179 IVQHTTDS SLEEKQR 3 26 - - 4 4 - - - - 5 3 5 5 - - - - - - - - S180 VQHTTDSS LEEKQRT 4 32 - - 4 4 - - - - 5 4 - - - - 7 1 - - 5 2 S198 GTSEIVKS PRIECSK 10 1326 106 - 83 61 82 88 35 - 108 62 103 94 106 97 83 19 97 40 53 9 S222 QLIMTRDS DGYENST 1 10 - - - - - - - - - - 5 5 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S75 LKRFYDLS DSDSNLS - - - - - - - - - - - S77 RFYDLSDS DSNLSGE - - - - - - - - - - - S79 YDLSDSDS NLSGEDS - - - - - - - - - - - S82 SDSDSNLS GEDSKAL 5.5e-5 - - - - - 5.5e-5 - - - - S134 NKTDLDNS IGIKKMK 0.52 - 7.6e-5 - - - -2.2e-3 - - - - S153 FKIDSNIS PKKDSKE 1.7e-114 - 2.3e-19 2.7e-30 - 2.7e-22 6.3e-34 6.6e-32 1.8e-5 0.22 1.8e-6 S179 IVQHTTDS SLEEKQR - - - - - - - - - - - S180 VQHTTDSS LEEKQRT - - - - - - - - - - - S198 GTSEIVKS PRIECSK 4.7e-61 - 1.2e-4 3.6e-27 - 5.2e-9 4.7e-26 1.3e-26 5.4e-6 -8.3e-3 - S222 QLIMTRDS DGYENST - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S75
S77
S79
S82
S134
S153
S179
S180
S198
S222
S228
T229
S290
S296
S298
T311
S312
S313
T319
S407
S442
T475
S614
S657
S663
Y671
T693
S694
S719
S735
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation CCRCC S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation COAD S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation GBM S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation HNSCC S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation LSCC S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation LUAD S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation OV S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation PDAC S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation UCEC S75 S77 S79 S82 S134 S153 S179 S180 S198 S222 S228 T229 S290 S296 S298 T311 S312 S313 T319 S407 S442 T475 S614 S657 S663 Y671 T693 S694 S719 S735 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S75
S77
S79
S82
S134
S153
S179
S180
S198
S222
S228
T229
S290
S296
S298
T311
S312
S313
T319
S407
S442
T475
S614
S657
S663
Y671
T693
S694
S719
S735
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S75
S77
S79
S82
S134
S153
S179
S180
S198
S222
S228
T229
S290
S296
S298
T311
S312
S313
T319
S407
S442
T475
S614
S657
S663
Y671
T693
S694
S719
S735
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.