GMIP: GEM interacting protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S19 PEGRKRYS DIFRSLD 10 651 38 - 13 12 45 36 46 - 62 34 39 36 54 50 34 8 70 27 35 12 S71 ASCWSGPS PEGPVPL 2 17 - - - - - - 9 - 5 3 - - - - - - - - - - S234 LRARSQGS PEDSAPQ 7 619 - - - - 85 85 99 - 21 13 30 28 - - 45 11 91 37 65 9 S238 SQGSPEDS APQASPG 2 26 - - - - 4 5 - - - - - - 9 8 - - - - - - S243 EDSAPQAS PGPSKQQ 4 91 23 - - - - - - - - - - - 9 8 12 5 - - 30 4 S256 QQERRRRS REEAQAK 6 308 - - - - - - 28 - - - 39 35 49 44 53 14 5 2 23 16 S365 PPPPPAFS FQEFLPS 1 9 9 - - - - - - - - - - - - - - - - - - - S372 SFQEFLPS LNSSPLD 1 31 31 - - - - - - - - - - - - - - - - - - - S375 EFLPSLNS SPLDIRK 1 8 - - - - - - - - - - - - 4 4 - - - - - - S376 FLPSLNSS PLDIRKK 6 200 - - - - 41 28 - - 35 17 5 4 21 22 - - 4 2 16 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S19 PEGRKRYS DIFRSLD -6.1e-6 - - -0.045 - 0.39 -1.5e-9 -2.0e-5 - 3.7e-5 -1.7e-4 S71 ASCWSGPS PEGPVPL - - - - - - - - - - - S234 LRARSQGS PEDSAPQ 6.5e-20 - - 4.3e-19 - 4.6e-3 1.4e-3 - -0.49 7.5e-10 - S238 SQGSPEDS APQASPG - - - - - - - - - - - S243 EDSAPQAS PGPSKQQ - - - - - - - - - - - S256 QQERRRRS REEAQAK -0.75 - - - - - -0.65 8.6e-3 8.2e-3 - -2.8e-5 S365 PPPPPAFS FQEFLPS - - - - - - - - - - - S372 SFQEFLPS LNSSPLD - - - - - - - - - - - S375 EFLPSLNS SPLDIRK - - - - - - - - - - - S376 FLPSLNSS PLDIRKK 0.57 - - 0.14 - -0.43 - 0.78 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S19
S71
S234
S238
S243
S256
S365
S372
S375
S376
S385
S396
T414
S421
S425
S430
S434
S437
T439
S440
S441
S454
T455
T457
S459
S460
S480
T660
S885
S886
S907
S914
S919
S923
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation CCRCC S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation COAD S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation GBM S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation HNSCC S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation LSCC S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation LUAD S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation OV S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation PDAC S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation UCEC S19 S71 S234 S238 S243 S256 S365 S372 S375 S376 S385 S396 T414 S421 S425 S430 S434 S437 T439 S440 S441 S454 T455 T457 S459 S460 S480 T660 S885 S886 S907 S914 S919 S923 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S19
S71
S234
S238
S243
S256
S365
S372
S375
S376
S385
S396
T414
S421
S425
S430
S434
S437
T439
S440
S441
S454
T455
T457
S459
S460
S480
T660
S885
S886
S907
S914
S919
S923
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S19
S71
S234
S238
S243
S256
S365
S372
S375
S376
S385
S396
T414
S421
S425
S430
S434
S437
T439
S440
S441
S454
T455
T457
S459
S460
S480
T660
S885
S886
S907
S914
S919
S923
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.