DLD: dihydrolipoamide dehydrogenase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1zmc chain A
1zmc chain B
1zmc chain C
1zmc chain D
1zmc chain E
1zmc chain F
1zmc chain G
1zmc chain H
1zmd chain A
1zmd chain B
1zmd chain C
1zmd chain D
1zmd chain E
1zmd chain F
1zmd chain G
1zmd chain H
1zy8 chain A
1zy8 chain B
1zy8 chain C
1zy8 chain D
1zy8 chain E
1zy8 chain F
1zy8 chain G
1zy8 chain H
1zy8 chain I
1zy8 chain J
2f5z chain A
2f5z chain B
2f5z chain C
2f5z chain D
2f5z chain E
2f5z chain F
2f5z chain G
2f5z chain H
2f5z chain I
2f5z chain J
3rnm chain A
3rnm chain B
3rnm chain C
3rnm chain D
5j5z chain A
5j5z chain B
5nhg chain A
5nhg chain B
5nhg chain C
5nhg chain D
5nhg chain E
5nhg chain F
5nhg chain G
5nhg chain H
6hg8 chain A
6hg8 chain B
6i4p chain A
6i4p chain B
6i4q chain A
6i4q chain B
6i4r chain A
6i4r chain B
6i4s chain A
6i4s chain B
6i4t chain A
6i4t chain B
6i4u chain A
6i4u chain B
6i4z chain A
6i4z chain B
6i4z chain C
6i4z chain D
6i4z chain E
6i4z chain F
6i4z chain G
6i4z chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y153 KVVHVNGY GKITGKN 1 9 - - - - - - 9 - - - - - - - - - - - - - S297 DVSIEAAS GGKAEVI 5 178 - - 66 47 - - - - 11 8 - - 9 8 - - 8 4 15 2 S502 REANLAAS FGKSINF 2 14 - - 4 4 - - - - - - - - - - - - 4 2 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y153 KVVHVNGY GKITGKN - - - - - - - - - - - S297 DVSIEAAS GGKAEVI -2.8e-5 - -2.8e-5 - - - - - - - - S502 REANLAAS FGKSINF - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y153
S297
S502
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y153 S297 S502 protein RNA SCNV methylation CCRCC Y153 S297 S502 protein RNA SCNV methylation COAD Y153 S297 S502 protein RNA SCNV methylation GBM Y153 S297 S502 protein RNA SCNV methylation HNSCC Y153 S297 S502 protein RNA SCNV methylation LSCC Y153 S297 S502 protein RNA SCNV methylation LUAD Y153 S297 S502 protein RNA SCNV methylation OV Y153 S297 S502 protein RNA SCNV methylation PDAC Y153 S297 S502 protein RNA SCNV methylation UCEC Y153 S297 S502 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y153
S297
S502
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y153
S297
S502
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.