Protein: ENSP00000216106
Gene: HMGXB4

LinkedOmicsKB © 2022-2023 Zhang Lab

HMGXB4:
HMG-box containing 4

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S79HKKKRKHSSDDYYYG7114----81035-73549871--125
S80KKKRKHSSDDYYYGD499----459---20192220------
S101SQKKKKKSSPQSTDT72319---7228-----4451103012659
S102QKKKKKSSPQSTDTA101246113-7362161190-8550103951101016015105449518
S118DLLKAITSPLAAGSK616715-----18-17104541----3216-
S197LKMKLILSPKEKGSS136----1620--------------
S205PKEKGSSSVDEESFQ849642-88--64-351868613228--1369518
Y213VDEESFQYPSQQATV15------------------5-
S480TTVKRKASSSEGSMK854755-----99-544340393741106324789
S497ASSVGVLSPQKKSPP101192113-4138142290-10862108999284831975319518
Showing 1 to 10 of 14 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S79HKKKRKHSSDDYYYG-----------
S80KKKRKHSSDDYYYGD0.36------0.920.16---
S101SQKKKKKSSPQSTDT1.3e-7-------2.9e-50.001-
S102QKKKKKSSPQSTDTA4e-20--3.1e-6--0.133.7e-261.1e-22-0.361.7e-80.02
S118DLLKAITSPLAAGSK0.12-----0.12----
S197LKMKLILSPKEKGSS-----------
S205PKEKGSSSVDEESFQ1.4e-3----0.372.0e-60.099---0.36
Y213VDEESFQYPSQQATV-----------
S480TTVKRKASSSEGSMK3.9e-4------0.74.7e-30.0418.9e-3-
S497ASSVGVLSPQKKSPP-0.49-0.036---0.557.2e-3-0.130.04-1.3e-50.15
Showing 1 to 10 of 14 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationCCRCCS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationCOADS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationGBMS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationHNSCCS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationLSCCS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationLUADS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationOVS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationPDACS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylationUCECS79S80S101S102S118S197S205Y213S480S497S502T505T506S512proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.