MYH9: myosin heavy chain 9
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2lnk chain C
3zwh chain Q
4cfq chain Q
4cfq chain R
4cfr chain Q
4eto chain P
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S36 KKLVWVPS DKSGFEP 8 320 37 - 22 18 - - 9 - 6 4 15 15 31 27 - - 38 15 65 18 S39 VWVPSDKS GFEPASL 7 289 - - 28 18 - - 10 - 17 11 30 28 62 57 - - 5 2 12 9 S45 KSGFEPAS LKEEVGE 6 150 - - 7 7 - - - - 13 6 5 4 17 17 - - 40 15 17 2 S197 YLAYVASS HKSKKDQ 5 120 8 - 8 8 - - - - 5 4 9 9 38 31 - - - - - - T552 KVMQEQGT HPKFQKP 4 143 33 - - - - - - - - - 10 9 43 41 - - 5 2 - - S628 LDQVAGMS ETALPGA 9 677 32 - 33 23 53 46 - - 67 40 73 68 97 89 6 - 11 5 32 2 T638 ALPGAFKT RKGMFRT 1 27 - - - - 15 12 - - - - - - - - - - - - - - T725 RQRYEILT PNSIPKG 9 1122 83 - 63 52 24 30 - - 97 55 108 99 88 82 74 17 105 44 83 18 S728 YEILTPNS IPKGFMD 5 121 - - - - - - - - 13 7 - - 9 7 8 1 48 22 6 - S751 IKALELDS NLYRIGQ 6 142 - - - - - - 9 - 23 12 15 12 21 20 12 4 - - 12 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S36 KKLVWVPS DKSGFEP 3.4e-4 - -0.007 - - - - 2.3e-3 - 4.5e-5 6.2e-3 S39 VWVPSDKS GFEPASL 0.18 - -0.7 - - - 0.32 0.09 - - - S45 KSGFEPAS LKEEVGE 0.05 - - - - - - - - 0.05 - S197 YLAYVASS HKSKKDQ 0.024 - - - - - - 0.024 - - - T552 KVMQEQGT HPKFQKP 0.03 - - - - - - 0.03 - - - S628 LDQVAGMS ETALPGA 0.026 - -0.005 2.5e-4 - 8.4e-3 -0.89 0.1 - - - T638 ALPGAFKT RKGMFRT - - - - - - - - - - - T725 RQRYEILT PNSIPKG 2.1e-15 - -0.013 0.98 - 1.7e-8 8.8e-17 0.016 -0.13 3.8e-10 1.3e-4 S728 YEILTPNS IPKGFMD 1.9e-3 - - - - - - - - 1.9e-3 - S751 IKALELDS NLYRIGQ 0.081 - - - - 0.82 - 0.025 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S36
S39
S45
S197
T552
S628
T638
T725
S728
S751
Y754
S841
T869
T873
S876
S957
T1005
T1006
S1057
T1058
S1114
S1122
S1126
T1151
S1154
S1195
T1221
S1243
T1269
S1290
S1292
S1294
S1297
S1304
S1308
T1313
S1326
S1340
S1398
Y1408
T1416
S1435
S1511
S1512
S1519
S1580
S1606
S1628
S1660
S1677
S1713
S1714
T1745
S1771
S1808
S1869
S1915
S1916
S1943
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation CCRCC S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation COAD S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation GBM S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation HNSCC S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation LSCC S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation LUAD S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation OV S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation PDAC S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation UCEC S36 S39 S45 S197 T552 S628 T638 T725 S728 S751 Y754 S841 T869 T873 S876 S957 T1005 T1006 S1057 T1058 S1114 S1122 S1126 T1151 S1154 S1195 T1221 S1243 T1269 S1290 S1292 S1294 S1297 S1304 S1308 T1313 S1326 S1340 S1398 Y1408 T1416 S1435 S1511 S1512 S1519 S1580 S1606 S1628 S1660 S1677 S1713 S1714 T1745 S1771 S1808 S1869 S1915 S1916 S1943 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S36
S39
S45
S197
T552
S628
T638
T725
S728
S751
Y754
S841
T869
T873
S876
S957
T1005
T1006
S1057
T1058
S1114
S1122
S1126
T1151
S1154
S1195
T1221
S1243
T1269
S1290
S1292
S1294
S1297
S1304
S1308
T1313
S1326
S1340
S1398
Y1408
T1416
S1435
S1511
S1512
S1519
S1580
S1606
S1628
S1660
S1677
S1713
S1714
T1745
S1771
S1808
S1869
S1915
S1916
S1943
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S36
S39
S45
S197
T552
S628
T638
T725
S728
S751
Y754
S841
T869
T873
S876
S957
T1005
T1006
S1057
T1058
S1114
S1122
S1126
T1151
S1154
S1195
T1221
S1243
T1269
S1290
S1292
S1294
S1297
S1304
S1308
T1313
S1326
S1340
S1398
Y1408
T1416
S1435
S1511
S1512
S1519
S1580
S1606
S1628
S1660
S1677
S1713
S1714
T1745
S1771
S1808
S1869
S1915
S1916
S1943
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.