Protein: ENSP00000216277

PAPOLA:: poly(A) polymerase alpha

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S10	FPVTTQGSQQTQPPQ	2	24	-	-	-	-	-	-	-	-	12	5	-	-	-	-	-	-	-	-	5	2
S24	QKHYGITSPISLAAP	10	1304	73	-	67	54	87	75	99	-	101	59	89	81	92	85	75	18	102	42	87	18
S27	YGITSPISLAAPKET	1	9	9	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S509	LQKKKKHSTEGVKLT	1	9	-	-	-	-	-	-	9	-	-	-	-	-	-	-	-	-	-	-	-	-
S526	NDSSLDLSMDSDNSM	4	61	35	-	4	4	4	5	-	-	-	-	-	-	5	4	-	-	-	-	-	-
S529	SLDLSMDSDNSMSVP	3	72	-	-	8	8	9	9	-	-	-	-	-	-	-	-	-	-	-	-	24	14
S532	LSMDSDNSMSVPSPT	3	68	-	-	8	8	4	5	-	-	-	-	-	-	-	-	-	-	-	-	36	7
S534	MDSDNSMSVPSPTSA	2	22	-	-	5	4	-	-	-	-	-	-	-	-	-	-	-	-	-	-	11	2
S537	DNSMSVPSPTSATKT	10	1080	88	-	30	28	61	56	90	-	79	46	98	91	100	93	30	4	54	19	95	18
S545	PTSATKTSPLNSSGS	9	975	13	-	-	-	92	96	91	-	36	20	78	72	71	64	76	17	96	40	95	18

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S10	FPVTTQGSQQTQPPQ	-	-	-	-	-	-	-	-	-	-	-
S24	QKHYGITSPISLAAP	2.3e-33	-	-1.6e-8	3.2e-23	-	4.8e-11	1.3e-26	2.8e-28	1.7e-4	-5.8e-8	1.6e-3
S27	YGITSPISLAAPKET	-	-	-	-	-	-	-	-	-	-	-
S509	LQKKKKHSTEGVKLT	-	-	-	-	-	-	-	-	-	-	-
S526	NDSSLDLSMDSDNSM	-	-	-	-	-	-	-	-	-	-	-
S529	SLDLSMDSDNSMSVP	0.5	-	-	-	-	-	-	-	-	-	0.5
S532	LSMDSDNSMSVPSPT	-	-	-	-	-	-	-	-	-	-	-
S534	MDSDNSMSVPSPTSA	-	-	-	-	-	-	-	-	-	-	-
S537	DNSMSVPSPTSATKT	4e-11	-	-0.026	0.99	-	0.016	6.1e-13	8.8e-10	-	0.058	0.04
S545	PTSATKTSPLNSSGS	4.4e-26	-	-	5e-10	-	1.9e-4	1.6e-24	3.6e-16	0.85	-4.8e-4	3.4e-3

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000216277Gene: PAPOLA

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000216277
Gene: PAPOLA