Protein: ENSP00000216554
Gene: EIF5

LinkedOmicsKB © 2022-2023 Zhang Lab

EIF5:
eukaryotic translation initiation factor 5

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S8MSVNVNRSVSDQFYR19------9-------------
S10VNVNRSVSDQFYRYK106448-44404182-32156458575447111468918
S79DRYIVNGSHEANKLQ127------------1512------
S121KKQTIGNSCKACGYR629117-1212--27---38366557----243
S149LKNPPENSDSGTGKK111----------------83--
S151NPPENSDSGTGKKEK327------9-----4572----
T153PENSDSGTGKKEKEK5223------81---55--2243614479
T178GSVSSSETPPPPPPP856555-54--52-734273367459--1346015
T194EINPPPHTMEEEEDD47417---------151188--105--
S220RRRMDEISDHAKVLT34619---------10854------
Showing 1 to 10 of 16 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S8MSVNVNRSVSDQFYR-----------
S10VNVNRSVSDQFYRYK5.4e-4--0.1-3.7e-37.2e-60.18-0.005-0.36
S79DRYIVNGSHEANKLQ-----------
S121KKQTIGNSCKACGYR2.9e-14-----3.0e-61.2e-9---
S149LKNPPENSDSGTGKK-----------
S151NPPENSDSGTGKKEK-----------
T153PENSDSGTGKKEKEK1.3e-3--------1.3e-3-
T178GSVSSSETPPPPPPP2.3e-23----5.3e-32e-112.2e-16--0.027
T194EINPPPHTMEEEEDD-----------
S220RRRMDEISDHAKVLT-----------
Showing 1 to 10 of 16 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationCCRCCS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationCOADS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationGBMS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationHNSCCS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationLSCCS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationLUADS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationOVS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationPDACS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylationUCECS8S10S79S121S149S151T153T178T194S220T227S229S389S390S410S419proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.