Protein: ENSP00000217026
Gene: MYBL2

LinkedOmicsKB © 2022-2023 Zhang Lab

MYBL2:
MYB proto-oncogene like 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S230SLLTNWPSVPPTIKE4429-44----63106--------
T234NWPSVPPTIKEEENS2149---------------32--
S241TIKEEENSEEELAAA8464--1616--90-905239371312143146584
T266TDLDAVRTPEPLEEF959953-1211--55-10862605418163571357218
S282KREDQEGSPPETSLP852964-----45-975455491081441069518
T286QEGSPPETSLPYKWV18--44----------------
S393RGELIPISPSTEVGG332----54----55------112
S395ELIPISPSTEVGGSG244--------2312--------72
T396LIPISPSTEVGGSGI219--------64--54------
S401PSTEVGGSGIGTPPS48815-------7220181412------
Showing 1 to 10 of 25 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S230SLLTNWPSVPPTIKE-----------
T234NWPSVPPTIKEEENS-----------
S241TIKEEENSEEELAAA2.7e-33----5.4e-186.4e-17----
T266TDLDAVRTPEPLEEF2.7e-19----1.1e-72.4e-18---0.13
S282KREDQEGSPPETSLP5.7e-17----8.6e-71.7e-13---0.027
T286QEGSPPETSLPYKWV-----------
S393RGELIPISPSTEVGG-----------
S395ELIPISPSTEVGGSG1.8e-3----1.8e-3-----
T396LIPISPSTEVGGSGI-----------
S401PSTEVGGSGIGTPPS4.4e-4-----4.4e-4----
Showing 1 to 10 of 25 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationCCRCCS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationCOADS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationGBMS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationHNSCCS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationLSCCS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationLUADS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationOVS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationPDACS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylationUCECS230T234S241T266S282T286S393S395T396S401T405S421T440S452S454S472S475T476T487T494T505T518T520T538S585proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.