TLR8: toll like receptor 8
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3w3g chain A
3w3g chain B
3w3j chain A
3w3j chain B
3w3k chain A
3w3k chain B
3w3l chain A
3w3l chain B
3w3l chain C
3w3l chain D
3w3m chain A
3w3n chain A
3w3n chain B
3wn4 chain A
4qbz chain A
4qbz chain B
4qc0 chain A
4qc0 chain B
4r07 chain A
4r07 chain B
4r07 chain C
4r07 chain D
4r08 chain A
4r08 chain B
4r08 chain C
4r08 chain D
4r09 chain A
4r09 chain B
4r09 chain C
4r09 chain D
4r0a chain A
4r6a chain A
4r6a chain B
5awa chain A
5awb chain A
5awc chain A
5awc chain B
5awc chain C
5awc chain D
5awd chain A
5az5 chain A
5az5 chain B
5az5 chain C
5az5 chain D
5hdh chain A
5wyx chain A
5wyx chain B
5wyz chain A
5wyz chain B
5z14 chain A
5z14 chain B
5z15 chain A
5z15 chain B
6kya chain A
6kya chain B
6ty5 chain A
6ty5 chain B
6v9u chain A
6v9u chain B
6wml chain A
6wml chain B
6wml chain C
6wml chain D
6zjz chain A
6zjz chain B
7crf chain A
7crf chain B
7r52 chain A
7r52 chain B
7r53 chain A
7r53 chain B
7r54 chain A
7r54 chain B
7rc9 chain A
7rc9 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S1037 YNNMYVDS IKQY___ 2 129 - - - - - - - - - - 14 13 54 48 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S1037 YNNMYVDS IKQY___ -1.3e-4 - - - - - - -1.3e-4 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S1037
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S1037 protein RNA SCNV methylation CCRCC S1037 protein RNA SCNV methylation COAD S1037 protein RNA SCNV methylation GBM S1037 protein RNA SCNV methylation HNSCC S1037 protein RNA SCNV methylation LSCC S1037 protein RNA SCNV methylation LUAD S1037 protein RNA SCNV methylation OV S1037 protein RNA SCNV methylation PDAC S1037 protein RNA SCNV methylation UCEC S1037 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S1037
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S1037
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.