MMP2: matrix metallopeptidase 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ck7 chain A
1cxw chain A
1eak chain A
1eak chain B
1eak chain C
1eak chain D
1gen chain A
1gxd chain A
1gxd chain B
1hov chain A
1j7m chain A
1ks0 chain A
1qib chain A
1rtg chain A
3ayu chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S434 YTKNFRLS QDDIKGI 3 23 - - - - - - - - 6 3 - - 5 4 - - 3 2 - - Y445 IKGIQELY GASPDID 3 23 - - - - - - - - 6 3 - - 5 4 - - 3 2 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S434 YTKNFRLS QDDIKGI - - - - - - - - - - - Y445 IKGIQELY GASPDID - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S434
Y445
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S434 Y445 protein RNA SCNV methylation CCRCC S434 Y445 protein RNA SCNV methylation COAD S434 Y445 protein RNA SCNV methylation GBM S434 Y445 protein RNA SCNV methylation HNSCC S434 Y445 protein RNA SCNV methylation LSCC S434 Y445 protein RNA SCNV methylation LUAD S434 Y445 protein RNA SCNV methylation OV S434 Y445 protein RNA SCNV methylation PDAC S434 Y445 protein RNA SCNV methylation UCEC S434 Y445 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S434
Y445
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S434
Y445
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.