MGA: MAX dimerization protein MGA
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S52 QDACALAS SVSSPVK 2 16 - - 4 4 - - - - - - - - 4 4 - - - - - - S55 CALASSVS SPVKSKG 1 9 - - - - - - - - - - - - - - - - 6 3 - - S56 ALASSVSS PVKSKGK 9 437 25 - - - 30 24 81 - 22 13 25 24 8 8 41 7 12 4 95 18 S277 DGKQKNSS DQEGNNI 3 71 - - - - 16 19 - - 7 3 - - - - 24 2 - - - - S340 LGFMDTDS ALSEVPQ 1 8 - - - - - - - - - - - - 4 4 - - - - - - S369 EDDSRVAS PLDQNGS 10 1211 105 - 90 70 7 2 99 - 103 58 104 95 101 92 53 14 75 30 95 18 T407 VTVKQEET DEETDVY 2 97 - - - - - - - - 52 31 - - - - - - - - 14 - Y414 TDEETDVY SNSDDDP 2 27 - - 9 8 - - - - - - 5 5 - - - - - - - - S415 DEETDVYS NSDDDPI 4 64 - - 4 4 - - - - 6 4 15 14 - - - - - - 6 11 S417 ETDVYSNS DDDPILE 3 73 - - 4 4 - - - - - - 15 14 - - - - - - 31 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S52 QDACALAS SVSSPVK - - - - - - - - - - - S55 CALASSVS SPVKSKG - - - - - - - - - - - S56 ALASSVSS PVKSKGK 8.3e-8 - - 5.1e-3 - 0.99 1.4e-9 - - - 0.065 S277 DGKQKNSS DQEGNNI - - - - - - - - - - - S340 LGFMDTDS ALSEVPQ - - - - - - - - - - - S369 EDDSRVAS PLDQNGS 0.34 - -1.2e-6 - - -1.8e-7 9.7e-18 3.7e-19 0.38 -4.4e-3 -0.066 T407 VTVKQEET DEETDVY 0.022 - - - - 0.022 - - - - - Y414 TDEETDVY SNSDDDP - - - - - - - - - - - S415 DEETDVYS NSDDDPI - - - - - - - - - - - S417 ETDVYSNS DDDPILE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S52
S55
S56
S277
S340
S369
T407
Y414
S415
S417
S448
S449
S534
S561
S569
S572
S576
S578
S607
T642
S645
T649
T758
S772
T850
S851
S879
S924
S989
S991
S1195
S1208
T1213
S1259
S1261
S1301
S1328
S1412
S1414
T1416
S1422
S1430
S1457
S1470
S1471
S1472
S1474
S1497
T1668
S1905
S2024
S2127
S2128
S2190
S2248
S2293
S2376
S2535
S2541
S2555
T2584
T2589
T2599
S2620
S2626
S2635
S2694
S2787
S2896
S2898
S2910
S2921
S2962
S2963
S2976
S2978
S3056
S3059
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation CCRCC S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation COAD S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation GBM S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation HNSCC S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation LSCC S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation LUAD S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation OV S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation PDAC S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation UCEC S52 S55 S56 S277 S340 S369 T407 Y414 S415 S417 S448 S449 S534 S561 S569 S572 S576 S578 S607 T642 S645 T649 T758 S772 T850 S851 S879 S924 S989 S991 S1195 S1208 T1213 S1259 S1261 S1301 S1328 S1412 S1414 T1416 S1422 S1430 S1457 S1470 S1471 S1472 S1474 S1497 T1668 S1905 S2024 S2127 S2128 S2190 S2248 S2293 S2376 S2535 S2541 S2555 T2584 T2589 T2599 S2620 S2626 S2635 S2694 S2787 S2896 S2898 S2910 S2921 S2962 S2963 S2976 S2978 S3056 S3059 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S52
S55
S56
S277
S340
S369
T407
Y414
S415
S417
S448
S449
S534
S561
S569
S572
S576
S578
S607
T642
S645
T649
T758
S772
T850
S851
S879
S924
S989
S991
S1195
S1208
T1213
S1259
S1261
S1301
S1328
S1412
S1414
T1416
S1422
S1430
S1457
S1470
S1471
S1472
S1474
S1497
T1668
S1905
S2024
S2127
S2128
S2190
S2248
S2293
S2376
S2535
S2541
S2555
T2584
T2589
T2599
S2620
S2626
S2635
S2694
S2787
S2896
S2898
S2910
S2921
S2962
S2963
S2976
S2978
S3056
S3059
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S52
S55
S56
S277
S340
S369
T407
Y414
S415
S417
S448
S449
S534
S561
S569
S572
S576
S578
S607
T642
S645
T649
T758
S772
T850
S851
S879
S924
S989
S991
S1195
S1208
T1213
S1259
S1261
S1301
S1328
S1412
S1414
T1416
S1422
S1430
S1457
S1470
S1471
S1472
S1474
S1497
T1668
S1905
S2024
S2127
S2128
S2190
S2248
S2293
S2376
S2535
S2541
S2555
T2584
T2589
T2599
S2620
S2626
S2635
S2694
S2787
S2896
S2898
S2910
S2921
S2962
S2963
S2976
S2978
S3056
S3059
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.