NEFM: neurofilament medium
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S22 RRVTETRS SFSRVSG 2 15 8 - - - - - - - - - - - - - - - - - 5 2 S23 RVTETRSS FSRVSGS 2 91 - - - - - - 81 - 7 3 - - - - - - - - - - S28 RSSFSRVS GSPSSGF 2 81 - - - - - - 63 - 10 8 - - - - - - - - - - S30 SFSRVSGS PSSGFRS 7 317 6 - 4 4 - - 99 - 90 54 10 7 - - - - 3 2 22 16 S32 SRVSGSPS SGFRSQS 1 27 - - - - - - 27 - - - - - - - - - - - - - S37 SPSSGFRS QSWSRGS 1 36 - - - - - - 36 - - - - - - - - - - - - - S39 SSGFRSQS WSRGSPS 1 9 - - - - - - 9 - - - - - - - - - - - - - S44 SQSWSRGS PSTVSSS 5 270 6 - 5 4 - - 99 - 94 53 5 4 - - - - - - - - S46 SWSRGSPS TVSSSYK 1 9 - - - - - - 9 - - - - - - - - - - - - - S49 RGSPSTVS SSYKRSM 2 17 - - 8 - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S22 RRVTETRS SFSRVSG - - - - - - - - - - - S23 RVTETRSS FSRVSGS - - - - - - - - - - - S28 RSSFSRVS GSPSSGF - - - - - - - - - - - S30 SFSRVSGS PSSGFRS -2.8e-17 - - - - -4.2e-13 - - - - -2.5e-6 S32 SRVSGSPS SGFRSQS - - - - - - - - - - - S37 SPSSGFRS QSWSRGS - - - - - - - - - - - S39 SSGFRSQS WSRGSPS - - - - - - - - - - - S44 SQSWSRGS PSTVSSS -7.8e-15 - - - - -7.7e-15 - - - - - S46 SWSRGSPS TVSSSYK - - - - - - - - - - - S49 RGSPSTVS SSYKRSM - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S22
S23
S28
S30
S32
S37
S39
S44
S46
S49
S50
S51
S69
S73
S74
S82
S88
S99
S142
T160
S214
S226
S281
S312
Y320
S328
S340
S346
S357
S418
T431
S433
S434
S467
S483
S511
S545
S553
S558
S559
T571
S592
T597
S615
S620
S628
S633
S667
S670
S672
S680
S685
S736
S783
S788
S821
T831
S837
S863
T889
T904
S905
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation CCRCC S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation COAD S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation GBM S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation HNSCC S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation LSCC S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation LUAD S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation OV S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation PDAC S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation UCEC S22 S23 S28 S30 S32 S37 S39 S44 S46 S49 S50 S51 S69 S73 S74 S82 S88 S99 S142 T160 S214 S226 S281 S312 Y320 S328 S340 S346 S357 S418 T431 S433 S434 S467 S483 S511 S545 S553 S558 S559 T571 S592 T597 S615 S620 S628 S633 S667 S670 S672 S680 S685 S736 S783 S788 S821 T831 S837 S863 T889 T904 S905 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S22
S23
S28
S30
S32
S37
S39
S44
S46
S49
S50
S51
S69
S73
S74
S82
S88
S99
S142
T160
S214
S226
S281
S312
Y320
S328
S340
S346
S357
S418
T431
S433
S434
S467
S483
S511
S545
S553
S558
S559
T571
S592
T597
S615
S620
S628
S633
S667
S670
S672
S680
S685
S736
S783
S788
S821
T831
S837
S863
T889
T904
S905
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S22
S23
S28
S30
S32
S37
S39
S44
S46
S49
S50
S51
S69
S73
S74
S82
S88
S99
S142
T160
S214
S226
S281
S312
Y320
S328
S340
S346
S357
S418
T431
S433
S434
S467
S483
S511
S545
S553
S558
S559
T571
S592
T597
S615
S620
S628
S633
S667
S670
S672
S680
S685
S736
S783
S788
S821
T831
S837
S863
T889
T904
S905
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.