Protein: ENSP00000221419
Gene: HNRNPL

LinkedOmicsKB © 2022-2023 Zhang Lab

HNRNPL:
heterogeneous nuclear ribonucleoprotein L

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S29PDEQRRRSGAMVKMA73699-----9-452544411616--10544132
Y48GGGGGRYYGGGSEGG118------18-------------
S52GRYYGGGSEGGRAPK101487122-10380919799-10862108991101014310105449015
T63RAPKRLKTDNAGDQH840828-2319--27-7288812219--4720205
Y92GGGGGENYDDPHKTP11414-------------------
T98NYDDPHKTPASPVVH19------9-------------
S101DPHKTPASPVVHIRG10958113-2727231399-108625954888133846217818
S185KISRPGDSDDSRSVN10123097-5937919799-8146989048457517100438918
S258LNGADIYSGCCTLKI511115-----9---551413----3911
S291DYTNPNLSGQGDPGS732042-124--27-4464572924----467
Showing 1 to 10 of 14 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S29PDEQRRRSGAMVKMA-0.53----0.99-0.23--0.93-
Y48GGGGGRYYGGGSEGG-----------
S52GRYYGGGSEGGRAPK2.7e-11-0.343.9e-7-3e-162.6e-122.5e-9-0.51-8.1e-6-1.4e-3
T63RAPKRLKTDNAGDQH-0.25-0.8----2.9e-31.5e-4--8.1e-4-
Y92GGGGGENYDDPHKTP-----------
T98NYDDPHKTPASPVVH-----------
S101DPHKTPASPVVHIRG-0.58--0.84-5.7e-5--0.351.3e-6-1.8e-7-0.0240.071
S185KISRPGDSDDSRSVN4.8e-28-0.0745.6e-17-8.1e-101.5e-171.9e-31.3e-3-3.8e-45.4e-4
S258LNGADIYSGCCTLKI4.2e-3---------4.2e-3
S291DYTNPNLSGQGDPGS-0.17------0.12-0.7---
Showing 1 to 10 of 14 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationCCRCCS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationCOADS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationGBMS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationHNSCCS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationLSCCS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationLUADS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationOVS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationPDACS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylationUCECS29Y48S52T63Y92T98S101S185S258S291S298Y375S381S589proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.