Protein: ENSP00000221554
Gene: CCDC130

LinkedOmicsKB © 2022-2023 Zhang Lab

CCDC130:
coiled-coil domain containing 130

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S40RERARKLSQGILIIR101071105-85729980-9152108991029226651214716
S238LKFHTLDSYEDKQKL512432-157--36-----1312----72
T285SRRTALATSPITVGD18----------------62--
S286RRTALATSPITVGDL1090081-7766191789-382573656964571431148318
S300LGIVRRRSRDVPESP65814---54--7254--81--8-
S306RSRDVPESPQHAADT824136---1088-643432--641352172
S332AAQDRPMSPGDCPPE101343105-7964575999-108628477106976717105449518
S362SRQDKPLSPAGSSQE94988-44717273-16111010--70151389518
S366KPLSPAGSSQEAADT232----------54------203
S367PLSPAGSSQEAADTP235----------1010------132
Showing 1 to 10 of 10 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S40RERARKLSQGILIIR-1.8e-5-1.3e-7---7.6e-7-1.5e-8-0.025-0.032-3.8e-7
S238LKFHTLDSYEDKQKL-----------
T285SRRTALATSPITVGD-----------
S286RRTALATSPITVGDL0.52-1e-7---0.0780.67-0.11-6.4e-50.25-0.21
S300LGIVRRRSRDVPESP-----------
S306RSRDVPESPQHAADT5.7e-3-----0.055-0.046--
S332AAQDRPMSPGDCPPE4.1e-5-1.3e-50.006-7.5e-61.1e-50.260.016-5.5e-11-0.17
S362SRQDKPLSPAGSSQE1.3e-7--6.1e-8----4.8e-5--0.74
S366KPLSPAGSSQEAADT-----------
S367PLSPAGSSQEAADTP-----------
Showing 1 to 10 of 10 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationCCRCCS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationCOADS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationGBMS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationHNSCCS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationLSCCS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationLUADS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationOVS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationPDACS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylationUCECS40S238T285S286S300S306S332S362S366S367proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.