ERF: ETS2 repressor factor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
7jsa chain J
7jsl chain E
7jsl chain H
7jsl chain J
7jsl chain L
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T3 _____MKT PADTGFA 8 279 9 - 13 12 9 9 90 - 6 3 - - 35 33 - - 23 9 23 5 T7 _MKTPADT GFAFPDW 1 17 17 - - - - - - - - - - - - - - - - - - - Y16 FAFPDWAY KPESSPG 5 168 93 - 21 20 - - 9 - - - - - 9 8 - - - - 5 3 S20 DWAYKPES SPGSRQI 9 156 - - 4 4 33 30 18 - 6 3 5 4 5 4 6 2 19 8 5 - S21 WAYKPESS PGSRQIQ 5 339 - - - - 30 32 81 - - - - - - - 34 7 73 31 48 3 S131 AGGAVPQS APPVPSG 8 387 69 - 21 20 6 3 45 - 61 34 19 17 45 40 5 2 - - - - S137 QSAPPVPS GGSHFRF 2 18 - - - - - - 9 - - - - - 5 4 - - - - - - T148 HFRFPPST PSEVLSP 4 90 - - - - 35 28 9 - - - - - 4 5 - - - - 7 2 S150 RFPPSTPS EVLSPTE 2 17 - - - - 4 5 - - - - - - - - - - - - 5 3 S154 STPSEVLS PTEDPRS 9 209 8 - 4 4 25 20 37 - 5 4 5 5 5 4 18 6 - - 48 11
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T3 _____MKT PADTGFA 1.2e-3 - - - - - - 1.2e-3 - - - T7 _MKTPADT GFAFPDW - - - - - - - - - - - Y16 FAFPDWAY KPESSPG 1.1e-5 - 1.1e-5 - - - - - - - - S20 DWAYKPES SPGSRQI 1.8e-7 - - 1.8e-7 - - - - - - - S21 WAYKPESS PGSRQIQ 1.3e-14 - - 1.2e-8 - - - - - 2e-7 - S131 AGGAVPQS APPVPSG -8e-8 - -0.67 - - -2.7e-5 - -2.9e-6 - - - S137 QSAPPVPS GGSHFRF - - - - - - - - - - - T148 HFRFPPST PSEVLSP -0.012 - - -0.012 - - - - - - - S150 RFPPSTPS EVLSPTE - - - - - - - - - - - S154 STPSEVLS PTEDPRS -2.8e-5 - - -2.2e-6 - - - - - - -0.23
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T3
T7
Y16
S20
S21
S131
S137
T148
S150
S154
T156
S161
S166
S168
S185
S187
S190
T193
S194
Y324
S327
T357
S363
S369
S373
S431
S435
T441
S444
S489
T526
S531
S532
T538
S542
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation CCRCC T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation COAD T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation GBM T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation HNSCC T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation LSCC T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation LUAD T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation OV T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation PDAC T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation UCEC T3 T7 Y16 S20 S21 S131 S137 T148 S150 S154 T156 S161 S166 S168 S185 S187 S190 T193 S194 Y324 S327 T357 S363 S369 S373 S431 S435 T441 S444 S489 T526 S531 S532 T538 S542 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T3
T7
Y16
S20
S21
S131
S137
T148
S150
S154
T156
S161
S166
S168
S185
S187
S190
T193
S194
Y324
S327
T357
S363
S369
S373
S431
S435
T441
S444
S489
T526
S531
S532
T538
S542
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T3
T7
Y16
S20
S21
S131
S137
T148
S150
S154
T156
S161
S166
S168
S185
S187
S190
T193
S194
Y324
S327
T357
S363
S369
S373
S431
S435
T441
S444
S489
T526
S531
S532
T538
S542
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.