Protein: ENSP00000223641
Gene: SEC61B

LinkedOmicsKB © 2022-2023 Zhang Lab

SEC61B:
SEC61 translocon subunit beta

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T5___MPGPTPSGTNVG35516---45------------255
S7_MPGPTPSGTNVGSS840735-4438349---53484641152--726
T9PGPTPSGTNVGSSGR324----------55----536-
S13PSGTNVGSSGRSPSK10120389-5947676863-7845938510696771597415918
S14SGTNVGSSGRSPSKA5167--44818--5228--2016152----
S17NVGSSGRSPSKAVAA10110470-869710099-8749746848468319105448318
S19GSSGRSPSKAVAARA19--------------81----
S29VAARAAGSTVRQRKN359------10-------1422310--
T48TRSAGRTTSAGTGGM216----------5443------
S49RSAGRTTSAGTGGMW9582--44676791-29171093433691638146614
Showing 1 to 10 of 12 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T5___MPGPTPSGTNVG-----------
S7_MPGPTPSGTNVGSS4.2e-34--3.4e-8--2.6e-161.7e-13---
T9PGPTPSGTNVGSSGR-----------
S13PSGTNVGSSGRSPSK3.4e-15-0.137.9e-9-8.2e-48.1e-204.3e-27-0.6-3e-12-0.46
S14SGTNVGSSGRSPSKA0.032----0.62-0.011---
S17NVGSSGRSPSKAVAA-0.19--7.9e-7--0.360.930.10.12-7.4e-10-3.9e-6
S19GSSGRSPSKAVAARA-----------
S29VAARAAGSTVRQRKN-0.02---------0.02-
T48TRSAGRTTSAGTGGM-----------
S49RSAGRTTSAGTGGMW0.017--3.4e-9-5.6e-5--0.27-0.50.17-2.3e-4
Showing 1 to 10 of 12 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationCCRCCT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationCOADT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationGBMT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationHNSCCT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationLSCCT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationLUADT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationOVT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationPDACT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylationUCECT5S7T9S13S14S17S19S29T48S49T52S63proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.