NUFIP2: nuclear FMR1 interacting protein 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T87 TLQQHQET PKKKTGY 10 1193 120 - 61 47 37 35 99 - 97 53 103 56 110 87 36 7 96 42 89 18 S107 NAGEREIS LKNLSSD 3 33 8 - 4 4 - - - - - - - - - - - - - - 8 9 S112 EISLKNLS SDEATNP 8 552 - - - - 52 55 63 - 67 41 30 27 4 4 48 11 61 23 48 18 S113 ISLKNLSS DEATNPI 7 118 18 - 4 4 - - 36 - 6 3 5 5 10 8 - - - - 19 - S134 NQQVVDTS LKQTVKA 1 8 - - - - - - - - - - - - - - - - - - 6 2 S172 GKSYENKS GENQSVD 2 79 25 - - - - - 54 - - - - - - - - - - - - - S177 NKSGENQS VDKSDTI 4 217 - - - - - - 90 - - - 45 40 20 16 - - 5 1 - - T192 PIPNGVVT NNSGYIT 1 10 - - - - - - - - 6 4 - - - - - - - - - - Y197 VVTNNSGY ITNGYMG 1 10 - - - - - - - - 6 4 - - - - - - - - - - T199 TNNSGYIT NGYMGKG 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T87 TLQQHQET PKKKTGY 4.2e-67 - 1.4e-3 5.1e-8 - 2.1e-14 3.1e-22 2.2e-27 - 3.1e-5 1.6e-6 S107 NAGEREIS LKNLSSD - - - - - - - - - - - S112 EISLKNLS SDEATNP 1.8e-20 - - 6.2e-13 - 4.9e-6 1e-9 - 0.74 1.1e-4 0.53 S113 ISLKNLSS DEATNPI - - - - - - - - - - - S134 NQQVVDTS LKQTVKA - - - - - - - - - - - S172 GKSYENKS GENQSVD - - - - - - - - - - - S177 NKSGENQS VDKSDTI 0.011 - - - - - 0.78 9.0e-4 - - - T192 PIPNGVVT NNSGYIT - - - - - - - - - - - Y197 VVTNNSGY ITNGYMG - - - - - - - - - - - T199 TNNSGYIT NGYMGKG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T87
S107
S112
S113
S134
S172
S177
T192
Y197
T199
S212
S214
S216
Y218
T219
T220
S250
S303
S304
S333
S376
T378
S379
S383
S384
S385
S386
S394
T571
S572
S582
S586
S588
S592
S608
S616
S629
T631
T633
S637
S652
S655
S692
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation CCRCC T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation COAD T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation GBM T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation HNSCC T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation LSCC T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation LUAD T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation OV T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation PDAC T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation UCEC T87 S107 S112 S113 S134 S172 S177 T192 Y197 T199 S212 S214 S216 Y218 T219 T220 S250 S303 S304 S333 S376 T378 S379 S383 S384 S385 S386 S394 T571 S572 S582 S586 S588 S592 S608 S616 S629 T631 T633 S637 S652 S655 S692 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T87
S107
S112
S113
S134
S172
S177
T192
Y197
T199
S212
S214
S216
Y218
T219
T220
S250
S303
S304
S333
S376
T378
S379
S383
S384
S385
S386
S394
T571
S572
S582
S586
S588
S592
S608
S616
S629
T631
T633
S637
S652
S655
S692
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T87
S107
S112
S113
S134
S172
S177
T192
Y197
T199
S212
S214
S216
Y218
T219
T220
S250
S303
S304
S333
S376
T378
S379
S383
S384
S385
S386
S394
T571
S572
S582
S586
S588
S592
S608
S616
S629
T631
T633
S637
S652
S655
S692
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.