COL1A1: collagen type I alpha 1 chain
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1q7d chain A
1q7d chain B
1q7d chain C
2llp chain A
2llp chain B
2llp chain C
3ejh chain E
3ejh chain F
3gxe chain E
3gxe chain F
5ctd chain A
5ctd chain C
5cti chain A
5cti chain C
5cva chain B
5cva chain C
5cva chain E
5cva chain F
5cvb chain A
5cvb chain B
5cvb chain C
5cvb chain D
5cvb chain E
5cvb chain F
5k31 chain A
5k31 chain B
5k31 chain C
5k31 chain D
5k31 chain E
5k31 chain F
5ou8 chain C
5ou8 chain D
5ou8 chain E
5ou9 chain C
5ou9 chain D
5ou9 chain E
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S171 SYGYDEKS TGGISVP 5 116 - - - - 4 5 - - - - - - 4 4 28 6 29 14 11 11 S176 EKSTGGIS VPGPMGP 9 879 90 - 4 4 93 95 - - 90 53 30 26 43 40 83 19 84 38 71 16 S214 EPGEPGAS GPMGPRG 6 333 5 - - - 78 83 - - - - - - 4 3 83 18 28 14 17 - S271 MKGHRGFS GLDGAKG 4 125 15 - - - 36 35 - - - - - - - - 26 8 3 2 - - S291 GPKGEPGS PGENGAP 7 455 83 - - - 97 100 - - 18 9 10 8 4 4 83 18 14 7 - - T328 ARGNDGAT GAAGPPG 1 27 - - - - 9 18 - - - - - - - - - - - - - - T337 AAGPPGPT GPAGPPG 6 211 6 - - - 38 43 - - - - - - 4 3 60 13 12 5 15 12 S363 GPQGPRGS EGPQGVR 2 128 - - - - 28 34 - - - - - - - - 55 11 - - - - S433 PPGPKGNS GEPGAPG 2 192 - - - - 63 80 - - - - - - - - 39 10 - - - - S441 GEPGAPGS KGDTGAK 2 116 - - - - 49 50 - - - - - - - - 15 2 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S171 SYGYDEKS TGGISVP 0.48 - - - - - - - - 0.48 - S176 EKSTGGIS VPGPMGP -2.2e-3 - - -4.5e-6 - -0.065 6e-7 0.15 -4.6e-6 -0.36 -9.3e-3 S214 EPGEPGAS GPMGPRG -1.8e-4 - - -2.6e-5 - - - - -1.1e-4 0.11 - S271 MKGHRGFS GLDGAKG -2.5e-18 - - -2.5e-18 - - - - - - - S291 GPKGEPGS PGENGAP -6.3e-8 - - -2.6e-6 - - - - -3.2e-3 - - T328 ARGNDGAT GAAGPPG - - - - - - - - - - - T337 AAGPPGPT GPAGPPG -1.6e-7 - - -1.1e-5 - - - - -2.6e-3 - - S363 GPQGPRGS EGPQGVR -1e-12 - - -2.9e-9 - - - - -3.4e-5 - - S433 PPGPKGNS GEPGAPG -2.1e-6 - - -1.2e-6 - - - - -0.064 - - S441 GEPGAPGS KGDTGAK 0.17 - - 0.17 - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S171
S176
S214
S271
S291
T328
T337
S363
S433
S441
T445
S513
S522
S543
S546
T553
S673
S720
S756
S784
T793
T874
S889
T913
S936
T948
S991
S1023
S1029
T1039
S1063
T1069
S1114
S1125
S1193
S1199
S1247
S1271
Y1274
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation CCRCC S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation COAD S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation GBM S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation HNSCC S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation LSCC S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation LUAD S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation OV S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation PDAC S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation UCEC S171 S176 S214 S271 S291 T328 T337 S363 S433 S441 T445 S513 S522 S543 S546 T553 S673 S720 S756 S784 T793 T874 S889 T913 S936 T948 S991 S1023 S1029 T1039 S1063 T1069 S1114 S1125 S1193 S1199 S1247 S1271 Y1274 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S171
S176
S214
S271
S291
T328
T337
S363
S433
S441
T445
S513
S522
S543
S546
T553
S673
S720
S756
S784
T793
T874
S889
T913
S936
T948
S991
S1023
S1029
T1039
S1063
T1069
S1114
S1125
S1193
S1199
S1247
S1271
Y1274
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S171
S176
S214
S271
S291
T328
T337
S363
S433
S441
T445
S513
S522
S543
S546
T553
S673
S720
S756
S784
T793
T874
S889
T913
S936
T948
S991
S1023
S1029
T1039
S1063
T1069
S1114
S1125
S1193
S1199
S1247
S1271
Y1274
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.