Protein: ENSP00000228307
Gene: PXN

LinkedOmicsKB © 2022-2023 Zhang Lab

PXN:
paxillin

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S83FIHQQPQSSSPVYGS214--44--------------6-
S84IHQQPQSSSPVYGSS7365--7360--9-6235555048--5211-
S85HQQPQSSSPVYGSSA7545--2422--99-342120183027--96419518
Y88PQSSSPVYGSSAKTS7599--4932--63-895458554540--53242413
S96GSSAKTSSVSNPQDS3106----------101044----699
S98SAKTSSVSNPQDSVG217--44--------54------
S103SVSNPQDSVGSPCSR334----------5454----511
S106NPQDSVGSPCSRVGE7800--1613--98-915264588477--98428918
S109DSVGSPCSRVGEEEH5244--3627------59541413--512411
Y118VGEEEHVYSFPNKQK71008--9176--72-10358103949285--105437313
Showing 1 to 10 of 49 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S83FIHQQPQSSSPVYGS-----------
S84IHQQPQSSSPVYGSS-1.8e-7--8.0e-6--2.3e-4--1.5e-16---
S85HQQPQSSSPVYGSSA-0.035--0.033--1.1e-4-3.4e-7-1.3e-13-5.3e-60.3
Y88PQSSSPVYGSSAKTS-1.4e-18--0.26---1.3e-5-1.2e-13-5.2e-12--0.32-0.46
S96GSSAKTSSVSNPQDS-----------
S98SAKTSSVSNPQDSVG-----------
S103SVSNPQDSVGSPCSR-----------
S106NPQDSVGSPCSRVGE-5.4e-7----0.92-8.5e-16-6.2e-13-0.0290.081
S109DSVGSPCSRVGEEEH-5.2e-7--0.18----7.5e-18---0.21
Y118VGEEEHVYSFPNKQK-2e-42--0.46---7.8e-6-7.8e-29-1.2e-21--8.5e-4-2.7e-5
Showing 1 to 10 of 49 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationCCRCCS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationCOADS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationGBMS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationHNSCCS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationLSCCS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationLUADS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationOVS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationPDACS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylationUCECS83S84S85Y88S96S98S103S106S109Y118S119S126S130T132S135T136S137S143S169S170S178Y181T186S188S216S219S226S227S230T236S243S244S250S258S260S261T263S272S302S303S320S321S322S332S336S340S343S513S533proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.