LTA4H: leukotriene A4 hydrolase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1gw6 chain A
1h19 chain A
1hs6 chain A
1sqm chain A
2r59 chain A
2vj8 chain A
3b7r chain L
3b7s chain A
3b7t chain A
3b7u chain X
3cho chain A
3chp chain A
3chq chain A
3chr chain A
3chs chain A
3fh5 chain A
3fh7 chain A
3fh8 chain A
3fhe chain A
3fts chain A
3ftu chain A
3ftv chain A
3ftw chain A
3ftx chain A
3fty chain A
3ftz chain A
3fu0 chain A
3fu3 chain A
3fu5 chain A
3fu6 chain A
3fud chain A
3fue chain A
3fuf chain A
3fuh chain A
3fui chain A
3fuj chain A
3fuk chain A
3ful chain A
3fum chain A
3fun chain A
3u9w chain A
4dpr chain A
4l2l chain A
4mkt chain A
4ms6 chain A
4r7l chain A
4rsy chain A
4rvb chain A
5aen chain A
5bpp chain A
5fwq chain A
5n3w chain A
5ni2 chain A
5ni4 chain A
5ni4 chain B
5ni4 chain C
5ni6 chain A
5nia chain A
5nid chain A
5nie chain A
5nie chain B
5nie chain C
6enb chain A
6enc chain A
6end chain A
6o5h chain A
6o5h chain B
6o5h chain C
7auz chain A
7av0 chain A
7av1 chain A
7av2 chain A
7kze chain A
7kze chain B
7kze chain C
7llq chain A
7llq chain B
7llq chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S15 CSLASPAS VCRTKHL 3 48 - - - - - - - - - - 9 9 9 8 - - - - 11 2 S27 KHLHLRCS VDFTRRT 3 79 7 - - - - - - - - - 19 19 18 16 - - - - - - S81 YALGERQS YKGSPME 1 35 - - - - - - 35 - - - - - - - - - - - - - S114 FETSPKSS ALQWLTP 1 9 - - - - - - - - - - - - 5 4 - - - - - - T179 SAIRDGET PDPEDPS 1 8 - - 4 4 - - - - - - - - - - - - - - - - S240 YEFSETES MLKIAED 3 85 - - 4 3 - - - - - - 24 21 18 15 - - - - - - S353 GWGELQNS VKTFGET 2 85 - - - - - - - - - - 9 8 35 33 - - - - - - Y384 VAYSSVPY EKGFALL 3 89 - - 4 4 - - - - - - 30 26 13 12 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S15 CSLASPAS VCRTKHL - - - - - - - - - - - S27 KHLHLRCS VDFTRRT - - - - - - - - - - - S81 YALGERQS YKGSPME - - - - - - - - - - - S114 FETSPKSS ALQWLTP - - - - - - - - - - - T179 SAIRDGET PDPEDPS - - - - - - - - - - - S240 YEFSETES MLKIAED -9.1e-8 - - - - - -9.1e-8 - - - - S353 GWGELQNS VKTFGET -9e-9 - - - - - - -9e-9 - - - Y384 VAYSSVPY EKGFALL -4.4e-11 - - - - - -4.4e-11 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S15
S27
S81
S114
T179
S240
S353
Y384
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation CCRCC S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation COAD S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation GBM S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation HNSCC S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation LSCC S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation LUAD S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation OV S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation PDAC S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation UCEC S15 S27 S81 S114 T179 S240 S353 Y384 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S15
S27
S81
S114
T179
S240
S353
Y384
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S15
S27
S81
S114
T179
S240
S353
Y384
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.