MTREX: Mtr4 exosome RNA helicase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6c90 chain A
6d6q chain M
6d6r chain M
6ieg chain A
6ieg chain B
6ieh chain B
6ro1 chain A
7s7b chain A
7s7b chain E
7s7c chain A
7s7c chain E
7z4y chain B
7z4y chain D
7z4z chain B
7z4z chain D
7z52 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S54 RFDGKLQS ESTNNGK 1 20 - - - - - - - - - - 10 10 - - - - - - - - T87 PRIEESIT EDLSLAD 1 8 - - - - - - - - - - - - 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S54 RFDGKLQS ESTNNGK - - - - - - - - - - - T87 PRIEESIT EDLSLAD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S54
T87
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S54 T87 protein RNA SCNV methylation CCRCC S54 T87 protein RNA SCNV methylation COAD S54 T87 protein RNA SCNV methylation GBM S54 T87 protein RNA SCNV methylation HNSCC S54 T87 protein RNA SCNV methylation LSCC S54 T87 protein RNA SCNV methylation LUAD S54 T87 protein RNA SCNV methylation OV S54 T87 protein RNA SCNV methylation PDAC S54 T87 protein RNA SCNV methylation UCEC S54 T87 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S54
T87
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S54
T87
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.