TNNC1: troponin C1, slow skeletal and cardiac type
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ap4 chain A
1ih0 chain A
1j1d chain A
1j1d chain D
1j1e chain A
1j1e chain D
1lxf chain C
1mxl chain C
1ozs chain A
1spy chain A
1wrk chain A
1wrk chain B
1wrl chain A
1wrl chain B
1wrl chain C
1wrl chain D
1wrl chain E
1wrl chain F
2jt0 chain A
2jt3 chain A
2jt8 chain A
2jtz chain A
2jxl chain A
2kdh chain A
2kfx chain T
2kgb chain C
2krd chain C
2l1r chain A
2l98 chain A
2mkp chain C
2mle chain C
2mlf chain C
2mzp chain C
2n79 chain C
2n7l chain C
3rv5 chain A
3rv5 chain B
3rv5 chain C
3rv5 chain D
3sd6 chain A
3swb chain A
4gje chain A
4gjf chain A
4gjg chain A
4y99 chain A
5vln chain A
5w88 chain A
5wcl chain A
6kn7 chain V
6kn7 chain c
6kn8 chain V
6kn8 chain c
6mv3 chain A
7jgi chain A
7sc2 chain A
7sc3 chain A
7sup chain A
7svc chain A
7swg chain A
7swi chain A
7sxc chain A
7sxd chain A
7uh9 chain A
7uha chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S93 KDDSKGKS EEELSDL 2 89 8 - - - - - - - 51 30 - - - - - - - - - - S98 GKSEEELS DLFRMFD 2 159 8 - - - - - - - 95 56 - - - - - - - - - - Y111 FDKNADGY IDLDELK 1 37 - - - - - - - - 21 16 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S93 KDDSKGKS EEELSDL -3.3e-3 - - - - -3.3e-3 - - - - - S98 GKSEEELS DLFRMFD -0.019 - - - - -0.019 - - - - - Y111 FDKNADGY IDLDELK -7.9e-5 - - - - -7.9e-5 - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S93
S98
Y111
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S93 S98 Y111 protein RNA SCNV methylation CCRCC S93 S98 Y111 protein RNA SCNV methylation COAD S93 S98 Y111 protein RNA SCNV methylation GBM S93 S98 Y111 protein RNA SCNV methylation HNSCC S93 S98 Y111 protein RNA SCNV methylation LSCC S93 S98 Y111 protein RNA SCNV methylation LUAD S93 S98 Y111 protein RNA SCNV methylation OV S93 S98 Y111 protein RNA SCNV methylation PDAC S93 S98 Y111 protein RNA SCNV methylation UCEC S93 S98 Y111 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S93
S98
Y111
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S93
S98
Y111
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.