NKTR: natural killer cell triggering receptor
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2he9 chain A
2he9 chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S243 KKRRKEAS SSEEPRN 10 307 23 - 19 19 37 43 18 - 12 7 10 9 28 23 13 3 25 8 10 - S244 KRRKEASS SEEPRNK 8 525 96 - 19 19 58 59 18 - - - 79 72 28 23 - - 34 14 6 - S245 RRKEASSS EEPRNKH 5 219 35 - - - - - 18 - - - 65 60 19 15 - - - - 5 2 S260 AMNPKGHS ERSDTNE 7 510 22 - - - 10 8 8 - - - 78 74 72 63 - - 85 34 40 16 S263 PKGHSERS DTNEKRS 8 539 23 - - - 24 29 99 - - - 20 18 72 63 16 3 93 38 27 14 S270 SDTNEKRS VDSSAKR 4 112 9 - - - - - 46 - - - - - - - - - 5 1 33 18 S320 PDVAPIVS DQKPSVS 1 8 - - - - - - - - - - - - - - 7 1 - - - - S325 IVSDQKPS VSKSGRK 1 21 - - - - - - - - - - - - - - - - - - 16 5 T343 RGTIRYHT PPRSRSC 1 19 - - - - - - - - - - - - - - - - - - 17 2 S347 RYHTPPRS RSCSESD 1 19 - - - - - - - - - - - - - - - - - - 17 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S243 KKRRKEAS SSEEPRN 3.6e-5 - - 1.2e-4 - - - 0.045 - - - S244 KRRKEASS SEEPRNK 1.3e-4 - - 9.3e-8 - - 1.9e-6 0.045 - -8.9e-6 - S245 RRKEASSS EEPRNKH 3.3e-7 - - - - - 3.3e-7 - - - - S260 AMNPKGHS ERSDTNE -3.8e-15 - - - - - -0.004 0.84 - -3.7e-12 -1.1e-9 S263 PKGHSERS DTNEKRS -1.9e-6 - - 0.061 - - -0.63 0.84 - -6.7e-12 -6.8e-8 S270 SDTNEKRS VDSSAKR -5.2e-6 - - - - - - - - - -5.2e-6 S320 PDVAPIVS DQKPSVS - - - - - - - - - - - S325 IVSDQKPS VSKSGRK - - - - - - - - - - - T343 RGTIRYHT PPRSRSC - - - - - - - - - - - S347 RYHTPPRS RSCSESD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S243
S244
S245
S260
S263
S270
S320
S325
T343
S347
Y375
S379
S390
S394
S401
S403
S406
S408
S410
Y411
S416
S463
S467
S468
S470
S471
S478
S518
S521
S523
S525
S572
S575
S611
S613
S663
S671
S673
T677
S733
S793
S809
S849
S866
S887
S889
S891
S940
S1045
S1061
S1062
S1077
S1138
T1145
S1146
T1155
S1203
S1331
S1335
S1337
T1403
S1420
S1422
Y1423
S1441
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation CCRCC S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation COAD S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation GBM S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation HNSCC S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation LSCC S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation LUAD S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation OV S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation PDAC S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation UCEC S243 S244 S245 S260 S263 S270 S320 S325 T343 S347 Y375 S379 S390 S394 S401 S403 S406 S408 S410 Y411 S416 S463 S467 S468 S470 S471 S478 S518 S521 S523 S525 S572 S575 S611 S613 S663 S671 S673 T677 S733 S793 S809 S849 S866 S887 S889 S891 S940 S1045 S1061 S1062 S1077 S1138 T1145 S1146 T1155 S1203 S1331 S1335 S1337 T1403 S1420 S1422 Y1423 S1441 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S243
S244
S245
S260
S263
S270
S320
S325
T343
S347
Y375
S379
S390
S394
S401
S403
S406
S408
S410
Y411
S416
S463
S467
S468
S470
S471
S478
S518
S521
S523
S525
S572
S575
S611
S613
S663
S671
S673
T677
S733
S793
S809
S849
S866
S887
S889
S891
S940
S1045
S1061
S1062
S1077
S1138
T1145
S1146
T1155
S1203
S1331
S1335
S1337
T1403
S1420
S1422
Y1423
S1441
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S243
S244
S245
S260
S263
S270
S320
S325
T343
S347
Y375
S379
S390
S394
S401
S403
S406
S408
S410
Y411
S416
S463
S467
S468
S470
S471
S478
S518
S521
S523
S525
S572
S575
S611
S613
S663
S671
S673
T677
S733
S793
S809
S849
S866
S887
S889
S891
S940
S1045
S1061
S1062
S1077
S1138
T1145
S1146
T1155
S1203
S1331
S1335
S1337
T1403
S1420
S1422
Y1423
S1441
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.