Protein: ENSP00000238714
Gene: PAPOLG

LinkedOmicsKB © 2022-2023 Zhang Lab

PAPOLG:
poly(A) polymerase gamma

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S23QKHYGITSPISLASP83139-44----392325235044267524111
S29TSPISLASPKEIDHI18------------------62
S508LQKKKKQSLSDVNRS1070645-108292599-31155954514528666288918
S525GLQSKRLSLDSSCLD107559-44665999-6941201812127518100428918
T537CLDSSRDTDNGTPFN19--54----------------
T541SRDTDNGTPFNSPAS232--44--------------186
S552SPASKSDSPSVGETE1061627-1212494164-342244403932681630145418
T597KVDSTVKTVSPPTVC221------9-----------12-
S599DSTVKTVSPPTVCTI734731-------84502018494361116262
T602VKTVSPPTVCTIPTV188-------------------
Showing 1 to 10 of 17 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S23QKHYGITSPISLASP3e-13----0.0912.4e-75e-7--6.9e-3
S29TSPISLASPKEIDHI-----------
S508LQKKKKQSLSDVNRS-0.11---0.85-8.2e-3-3.1e-3-0.12-0.44-8.8e-3
S525GLQSKRLSLDSSCLD-0.28---3.4e-7-2.7e-30.29-0.115.6e-3-0.5
T537CLDSSRDTDNGTPFN-----------
T541SRDTDNGTPFNSPAS-----------
S552SPASKSDSPSVGETE2.7e-18--1.7e-10-6.3e-42.4e-181.8e-9-0.48-1.1e-30.012
T597KVDSTVKTVSPPTVC-----------
S599DSTVKTVSPPTVCTI2.3e-3----0.570.0220.015---
T602VKTVSPPTVCTIPTV-----------
Showing 1 to 10 of 17 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationCCRCCS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationCOADS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationGBMS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationHNSCCS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationLSCCS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationLUADS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationOVS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationPDACS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylationUCECS23S29S508S525T537T541S552T597S599T602S646S648S650S684S708S715S716proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.