Protein: ENSP00000239243
Gene: MSX2

LinkedOmicsKB © 2022-2023 Zhang Lab

MSX2:
msh homeobox 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S12SKGNDLFSPDEEGPA16------------------6-
S44ERRVKVSSLPFSVEA18------------------62
S63KKPPKEASPLPAESA37928-------63--------357
S91HGAREAHSPGPLVKP9964122-27245750--1025973666051153100429518
S109ASVKSENSEDGAAWM117------------------134
Y122WMQEPGRYSPPPRHM23226-----------------6-
S123MQEPGRYSPPPRHMS411718---810----54------5418
S130SPPPRHMSPTTCTLR39630---------54------4215
Showing 1 to 8 of 8 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S12SKGNDLFSPDEEGPA-----------
S44ERRVKVSSLPFSVEA-----------
S63KKPPKEASPLPAESA-----------
S91HGAREAHSPGPLVKP1.6e-33-8.2e-87e-7-5.4e-49.1e-132.4e-9-1e-8-0.49
S109ASVKSENSEDGAAWM-----------
Y122WMQEPGRYSPPPRHM-----------
S123MQEPGRYSPPPRHMS-0.83----------0.83
S130SPPPRHMSPTTCTLR0.79---------0.79
Showing 1 to 8 of 8 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationCCRCCS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationCOADS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationGBMS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationHNSCCS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationLSCCS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationLUADS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationOVS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationPDACS12S44S63S91S109Y122S123S130proteinRNASCNVmethylationUCECS12S44S63S91S109Y122S123S130proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.