Protein: ENSP00000240316
Gene: COIL

LinkedOmicsKB © 2022-2023 Zhang Lab

COIL:
coilin

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T122QLEEGEETEPDCKYS101483113-9976909871-10359108991101018319105449015
S202KKAKNPKSPKVQAVK199-------------------
S217DWANQRCSSPKGSAR17----------------52--
S235VKAKRKGSVSVCSKE9732--88423044-723974664036691678346313
S237AKRKGSVSVCSKESP113----------------94--
S240KGSVSVCSKESPSSS5333--2726----8647--4541--26926-
S271VTLEARNSSEKLPTE9122498-103807883--7645989097887115100404418
S301LAIKLGFSLTPSKGK188-------------------
T303IKLGFSLTPSKGKTS101311113-6147695772-108621089410696811582338918
S305LGFSLTPSKGKTSGT632346-2117------25237264--73405
Showing 1 to 10 of 19 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T122QLEEGEETEPDCKYS0.031-3.4e-36e-15--0.0817.0e-5-0.68-0.69-0.02-1.9e-4
S202KKAKNPKSPKVQAVK-----------
S217DWANQRCSSPKGSAR-----------
S235VKAKRKGSVSVCSKE1.8e-13--0.026-0.0888.9e-151.3e-141.6e-3-3.8e-60.12
S237AKRKGSVSVCSKESP-----------
S240KGSVSVCSKESPSSS5.6e-6--1.2e-3--1.4e-7-4.7e-9---
S271VTLEARNSSEKLPTE-0.33--2.4e-222.2e-16-0.0186.3e-30.350.11-5.6e-6-0.73
S301LAIKLGFSLTPSKGK-----------
T303IKLGFSLTPSKGKTS5.9e-84-2.5e-81.2e-10-1.6e-175.3e-335.2e-274.0e-56.7e-62.5e-3
S305LGFSLTPSKGKTSGT3.4e-6-0.012---2.0e-60.43---
Showing 1 to 10 of 19 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationCCRCCT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationCOADT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationGBMT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationHNSCCT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationLSCCT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationLUADT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationOVT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationPDACT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylationUCECT122S202S217S235S237S240S271S301T303S305S382T456S487Y488S489S566S568T570S571proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.