MAPK8IP1: mitogen-activated protein kinase 8 interacting protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2g01 chain F
2g01 chain G
2gmx chain F
2gmx chain G
2h96 chain F
2h96 chain G
3oxi chain J
3ptg chain J
3vud chain F
3vug chain F
3vuh chain F
3vui chain F
3vuk chain F
3vul chain F
3vum chain F
4e73 chain B
4g1w chain B
4h39 chain B
4hys chain B
4hyu chain B
4izy chain B
5lw1 chain C
5lw1 chain F
5lw1 chain I
6fuz chain A
7nyk chain AAA
7nyk chain BBB
7nyk chain CCC
7nyk chain DDD
7nyl chain AAA
7nyl chain BBB
7nym chain AAA
7nym chain BBB
7nym chain CCC
7nym chain DDD
7nyn chain AAA
7nyn chain BBB
7nyn chain CCC
7nyn chain DDD
7nyn chain EEE
7nyn chain FFF
7nyn chain GGG
7nyn chain HHH
7nyn chain III
7nyn chain JJJ
7nyn chain KKK
7nyn chain LLL
7nyo chain AAA
7nyo chain BBB
7nyo chain CCC
7nyo chain DDD
7nzb chain AAA
7nzb chain BBB
7nzb chain CCC
7nzb chain DDD
7nzb chain EEE
7nzb chain FFF
7nzb chain GGG
7nzb chain HHH
7nzb chain III
7nzb chain JJJ
7nzb chain KKK
7nzb chain LLL
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S15 GLGGGAAS PPAASPF 1 53 - - - - - - 53 - - - - - - - - - - - - - S29 FLGLHIAS PPNFRLT 1 55 - - - - - - 55 - - - - - - - - - - - - - S181 QDTLNNNS LGKKHSW 1 64 - - - - - - 64 - - - - - - - - - - - - - S187 NSLGKKHS WQDRVSR 2 45 - - - - - - 36 - - - - - - - - - 6 3 - - S195 WQDRVSRS SSPLKTG 1 9 - - - - - - 9 - - - - - - - - - - - - - T205 PLKTGEQT PPHEHIC 1 99 - - - - - - 99 - - - - - - - - - - - - - S214 PHEHICLS DELPPQS 1 81 - - - - - - 81 - - - - - - - - - - - - - S235 DRGTSTDS PCRRSTA 4 211 - - - - - - 99 - - - - - - - 55 11 7 2 33 4 T284 ATEEIYLT PVQRPPD 1 19 - - - - - - 19 - - - - - - - - - - - - - S330 GRPHPSIS EEEEGFD 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S15 GLGGGAAS PPAASPF - - - - - - - - - - - S29 FLGLHIAS PPNFRLT - - - - - - - - - - - S181 QDTLNNNS LGKKHSW - - - - - - - - - - - S187 NSLGKKHS WQDRVSR - - - - - - - - - - - S195 WQDRVSRS SSPLKTG - - - - - - - - - - - T205 PLKTGEQT PPHEHIC - - - - - - - - - - - S214 PHEHICLS DELPPQS - - - - - - - - - - - S235 DRGTSTDS PCRRSTA 0.013 - - - - - - - 0.013 - - T284 ATEEIYLT PVQRPPD - - - - - - - - - - - S330 GRPHPSIS EEEEGFD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S15
S29
S181
S187
S195
T205
S214
S235
T284
S330
S340
S341
S355
S366
S473
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation CCRCC S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation COAD S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation GBM S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation HNSCC S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation LSCC S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation LUAD S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation OV S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation PDAC S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation UCEC S15 S29 S181 S187 S195 T205 S214 S235 T284 S330 S340 S341 S355 S366 S473 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S15
S29
S181
S187
S195
T205
S214
S235
T284
S330
S340
S341
S355
S366
S473
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S15
S29
S181
S187
S195
T205
S214
S235
T284
S330
S340
S341
S355
S366
S473
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.