Protein: ENSP00000241704
Gene: COPA

LinkedOmicsKB © 2022-2023 Zhang Lab

COPA:
COPI coat complex subunit alpha

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S16SARVKGLSFHPKRPW17------------43------
S173GLRKKNLSPGAVESD99059---929681-7947484524208319105449518
Y249VDTCRGHYNNVSCAV292------72---------155--
S349RQLDFNSSKDVAVMQ127----------------189--
S384VLLCTRASNLENSTY18------------44------
S402TIPKDADSQNPDAPE101432121-9168899090-1086298851101006113105447918
S434AVLDRMHSLLIKNLK224------18-----------6-
T591ECRPRVLTIDPTEFK847587-124----169504562557138205316
S756LKNCGQKSLAYLTAA214------------44----6-
S773GLDEEAESLKETFDP72006-3128--9-42231512----123109
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S16SARVKGLSFHPKRPW-----------
S173GLRKKNLSPGAVESD1.1e-41--1.1e-25-1.5e-124.1e-112.8e-40.74.8e-62.3e-3
Y249VDTCRGHYNNVSCAV-----------
S349RQLDFNSSKDVAVMQ-----------
S384VLLCTRASNLENSTY-----------
S402TIPKDADSQNPDAPE5.3e-23--0.31.4e-11-2.8e-51.8e-261.1e-16-0.052-2.0e-68.1e-9
S434AVLDRMHSLLIKNLK-----------
T591ECRPRVLTIDPTEFK1.2e-6-----2.3e-101.0e-5--1.8e-30.039
S756LKNCGQKSLAYLTAA-----------
S773GLDEEAESLKETFDP0.22-0.038---0.74-----
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationCCRCCS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationCOADS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationGBMS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationHNSCCS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationLSCCS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationLUADS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationOVS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationPDACS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylationUCECS16S173Y249S349S384S402S434T591S756S773T806S824S895S915T917S924S1146S1193T1205S1219proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.