LRP1: LDL receptor related protein 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1cr8 chain A
1d2l chain A
1j8e chain A
2fyj chain A
2fyl chain B
2knx chain A
2kny chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T241 DFSYANET VCWVHVG 1 9 - - - - - - - - - - - - - - - - 7 2 - - S942 TCPPNQFS CASGRCI 1 7 - - - - - - 7 - - - - - - - - - - - - - S945 PNQFSCAS GRCIPIS 1 7 - - - - - - 7 - - - - - - - - - - - - - S1024 STQFKCNS GRCIPEH 1 9 - - - - - - 9 - - - - - - - - - - - - - T2474 IIAVANDT NSCELSP 1 9 - - - - - - - - - - - - 5 4 - - - - - - S2476 AVANDTNS CELSPCR 1 9 - - - - - - - - - - - - 5 4 - - - - - - T2496 CQDLCLLT HQGHVNC 4 40 18 - - - 3 6 8 - - - - - - - - - - - 5 - S2504 HQGHVNCS CRGGRIL 4 40 18 - - - 3 6 8 - - - - - - - - - - - 5 - T2516 RILQDDLT CRAVNSS 4 40 18 - - - 3 6 8 - - - - - - - - - - - 5 - S2595 ADDCGDGS DEIPCNK 1 5 - - - - - - - - - - - - - - - - 3 2 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T241 DFSYANET VCWVHVG - - - - - - - - - - - S942 TCPPNQFS CASGRCI - - - - - - - - - - - S945 PNQFSCAS GRCIPIS - - - - - - - - - - - S1024 STQFKCNS GRCIPEH - - - - - - - - - - - T2474 IIAVANDT NSCELSP - - - - - - - - - - - S2476 AVANDTNS CELSPCR - - - - - - - - - - - T2496 CQDLCLLT HQGHVNC - - - - - - - - - - - S2504 HQGHVNCS CRGGRIL - - - - - - - - - - - T2516 RILQDDLT CRAVNSS - - - - - - - - - - - S2595 ADDCGDGS DEIPCNK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T241
S942
S945
S1024
T2474
S2476
T2496
S2504
T2516
S2595
S2683
Y2814
S2816
T2817
S2950
S2953
S3253
S3461
T3463
S3604
S3642
S4358
T4362
T4366
T4460
T4500
S4517
S4520
S4523
T4524
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation CCRCC T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation COAD T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation GBM T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation HNSCC T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation LSCC T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation LUAD T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation OV T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation PDAC T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation UCEC T241 S942 S945 S1024 T2474 S2476 T2496 S2504 T2516 S2595 S2683 Y2814 S2816 T2817 S2950 S2953 S3253 S3461 T3463 S3604 S3642 S4358 T4362 T4366 T4460 T4500 S4517 S4520 S4523 T4524 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T241
S942
S945
S1024
T2474
S2476
T2496
S2504
T2516
S2595
S2683
Y2814
S2816
T2817
S2950
S2953
S3253
S3461
T3463
S3604
S3642
S4358
T4362
T4366
T4460
T4500
S4517
S4520
S4523
T4524
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T241
S942
S945
S1024
T2474
S2476
T2496
S2504
T2516
S2595
S2683
Y2814
S2816
T2817
S2950
S2953
S3253
S3461
T3463
S3604
S3642
S4358
T4362
T4366
T4460
T4500
S4517
S4520
S4523
T4524
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.