- NAGK:
- N-acetylglucosamine kinase
Lollipop plot
Phosphosites location and occurrence
Structure
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Site
| Sequence | Cohorts | Total | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N | T | N |
S74 | PLRSLGLSLSGGDQE | 8 | 1224 | - | - | 103 | 80 | 71 | 73 | 99 | - | 92 | 54 | 103 | 95 | 105 | 97 | - | - | 98 | 41 | 95 | 18 |
S76 | RSLGLSLSGGDQEDA | 8 | 1305 | - | - | 103 | 80 | 87 | 92 | 99 | - | 108 | 62 | 108 | 99 | 110 | 101 | - | - | 101 | 42 | 95 | 18 |
Tumor and normal comparison
Site
| Sequence | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
---|---|---|---|---|---|---|---|---|---|---|---|---|
S74 | PLRSLGLSLSGGDQE | -2.2e-21 | - | 8.1e-16 | -2.4e-11 | - | -3.8e-16 | -8.3e-15 | -8.6e-12 | - | -3.7e-4 | -0.82 |
S76 | RSLGLSLSGGDQEDA | 0.76 | - | 2e-16 | -9.6e-12 | - | 0.37 | -0.058 | -0.56 | - | -0.23 | 0.028 |
Phenotype and mutation association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phenotype | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
ESTIMATE: ESTIMATEScore | S76 | 2.4e-35 | - | 0.012 | 1.7e-5 | 2.8e-6 | 2.5e-3 | 2.2e-16 | 2.1e-5 | - | 1.5e-3 | 8.2e-7 |
ESTIMATE: ImmuneScore | S76 | 2.2e-34 | - | 5.7e-6 | 1.2e-3 | 4.0e-6 | 2.3e-3 | 2.2e-16 | 5.9e-7 | - | 0.021 | 2.7e-4 |
HALLMARK_COMPLEMENT | S76 | 9.6e-32 | - | 7.5e-4 | 2.6e-5 | 1.4e-5 | 5.4e-3 | 2.2e-16 | 2.9e-4 | - | 0.043 | 4.0e-6 |
xcell: immune score | S76 | 1.4e-30 | - | 2.4e-4 | 5.1e-3 | 4.8e-6 | 4.2e-5 | 2.2e-16 | 9.8e-6 | - | 0.015 | 0.021 |
HALLMARK_ALLOGRAFT_REJECTION | S76 | 4.1e-30 | - | 2.1e-5 | 6.5e-4 | 5.1e-5 | 2.5e-3 | 2.2e-16 | 1.3e-6 | - | 0.037 | 0.018 |
xcell: microenvironment score | S76 | 5.9e-30 | - | 7.2e-3 | 1.4e-3 | 1.9e-5 | 5.1e-4 | 2.2e-16 | 2.2e-4 | - | 5.5e-3 | 1.2e-4 |
HALLMARK_IL2_STAT5_SIGNALING | S76 | 1.3e-28 | - | 2.8e-3 | 7.5e-5 | 1.7e-4 | 5.7e-3 | 2.2e-16 | 8.3e-5 | - | 0.18 | 9.9e-6 |
HALLMARK_IL6_JAK_STAT3_SIGNALING | S76 | 5.3e-26 | - | 1.9e-4 | 4.5e-3 | 2.4e-4 | 8.7e-3 | 2.2e-16 | 2.3e-6 | - | 0.18 | 0.007 |
HALLMARK_INFLAMMATORY_RESPONSE | S76 | 2.3e-25 | - | 1.8e-3 | 3.2e-4 | 6.1e-5 | 8.2e-3 | 2.2e-16 | 4.6e-5 | - | 0.16 | 0.018 |
xcell: Macrophage M1 | S76 | 2.5e-25 | - | 1.1e-3 | 8.2e-4 | 1.1e-5 | 0.013 | 2.2e-16 | 3.8e-6 | - | 0.25 | 0.051 |
Cis-association
Kinase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |
Phosphatase association
Signed p-values | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphatase | Site | Meta P | BRCA | CCRCC | COAD | GBM | HNSCC | LSCC | LUAD | OV | PDAC | UCEC |
No matching records found |