Protein: ENSP00000244426
Gene: FBXO9

LinkedOmicsKB © 2022-2023 Zhang Lab

FBXO9:
F-box protein 9

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S33DDDEENESPAETDLQ476------9---201889----12-
S136FKITYTRSPDGDGVG576--44--18---191843--51--
S145DGDGVGNSYIEDNDD19--------63----------
Showing 1 to 3 of 3 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S33DDDEENESPAETDLQ-0.016------0.016----
S136FKITYTRSPDGDGVG-----------
S145DGDGVGNSYIEDNDD-----------
Showing 1 to 3 of 3 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
HALLMARK_UV_RESPONSE_UPS330.038-----0.034---0.42
HALLMARK_UV_RESPONSE_DNS330.043-----0.085---0.26
SBS1 (clock-like)S1360.045---0.098-0.24----
HALLMARK_APOPTOSISS330.051-----0.19---0.15
xcell: Common lymphoid progenitorS330.059-----0.14---0.23
xcell: T cell CD8+ naiveS330.068-----0.4---0.083
HALLMARK_TNFA_SIGNALING_VIA_NFKBS330.071-----0.25---0.16
HALLMARK_KRAS_SIGNALING_UPS330.078-----0.25---0.18
KINASE-PSP_MAPKAPK2S330.087-----0.18---0.28
xcell: MonocyteS330.099-----0.22---0.27
Showing 1 to 10 of 774 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS33S136S145proteinRNASCNVmethylationCCRCCS33S136S145proteinRNASCNVmethylationCOADS33S136S145proteinRNASCNVmethylationGBMS33S136S145proteinRNASCNVmethylationHNSCCS33S136S145proteinRNASCNVmethylationLSCCS33S136S145proteinRNASCNVmethylationLUADS33S136S145proteinRNASCNVmethylationOVS33S136S145proteinRNASCNVmethylationPDACS33S136S145proteinRNASCNVmethylationUCECS33S136S145proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
ROS1S331.6e-3-----1.6e-3----
PRKD2S1363.1e-3---0.028-0.047----
MAST4S1360.005---0.18-8.6e-3----
IRAK3S335.7e-3-----0.17---0.011
EGFRS1366.9e-3---6.5e-3-0.27----
NEK11S1367.8e-3---0.029-0.11----
MAP4K4S1367.9e-3---0.013-0.2----
ADCK2S330.009-----0.009----
LRRK2S330.01-----0.45---4.1e-3
NME9S330.011-----0.011----
Showing 1 to 10 of 1614 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
CDC25BS33-5.5e-4------5.5e-4----
DUSP19S136-6.9e-3----0.12--0.022----
MTMR7S136-0.007----0.007------
PDP1S33-8.6e-3------2.2e-3----0.51
PPM1DS33-0.016------0.016----
PPM1HS33-0.023------0.12----0.094
MINPP1S136-0.025----2.5e-3--0.89----
BPGMS136-0.025----0.014--0.48----
PTPDC1S136-0.028----0.028------
PDP2S136-0.03----0.22--0.066----
Showing 1 to 10 of 720 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.