Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3o2q chain A
3o2q chain D
3o2s chain A
3o2t chain A
3odr chain A
3ods chain A
4h3h chain A
4h3h chain D
4h3k chain A
4h3k chain D
6v4x chain J
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S13 GDSVTRRS VASQFFT 2 49 - - - - - - - - - - 5 5 - - - - - - 24 15 T20 SVASQFFT QEEGPGI 1 9 - - - - - - - - - - - - - - - - - - 7 2 S353 RKRPRDDS DSTLKKM 3 79 - - - - - - - - - - 9 9 5 4 - - - - 41 11 S494 VLIKRRLS AQGQAIS 10 1508 113 - 103 80 97 100 99 - 108 62 108 99 110 101 75 18 105 44 70 16 S501 SAQGQAIS VVGSLSS 2 33 7 - - - - - - - - - - - 14 12 - - - - - - S505 QAISVVGS LSSMSPL 3 32 8 - 8 8 - - - - - - 4 4 - - - - - - - - S507 ISVVGSLS SMSPLEE 8 160 17 - 11 11 4 5 9 - 13 6 20 18 18 16 - - - - 10 2 S508 SVVGSLSS MSPLEEE 1 9 - - - - 4 5 - - - - - - - - - - - - - - S510 VGSLSSMS PLEEEAP 9 288 17 - 20 19 10 8 36 - 41 26 9 9 4 4 - - 13 8 48 16 S870 LTDKVPPS PELVKRV 2 17 - - 4 4 - - - - 5 4 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S13 GDSVTRRS VASQFFT 0.091 - - - - - - - - - 0.091 T20 SVASQFFT QEEGPGI - - - - - - - - - - - S353 RKRPRDDS DSTLKKM 0.085 - - - - - - - - - 0.085 S494 VLIKRRLS AQGQAIS 0.75 - 5.9e-22 -5.6e-9 - -3.4e-7 -0.33 0.002 0.019 -0.49 -0.049 S501 SAQGQAIS VVGSLSS - - - - - - - - - - - S505 QAISVVGS LSSMSPL - - - - - - - - - - - S507 ISVVGSLS SMSPLEE 0.57 - - - - - 0.57 - - - - S508 SVVGSLSS MSPLEEE - - - - - - - - - - - S510 VGSLSSMS PLEEEAP -3.3e-10 - -1.6e-5 - - -3.9e-7 - - - - -0.14 S870 LTDKVPPS PELVKRV - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S13
T20
S353
S494
S501
S505
S507
S508
S510
S870
T1083
S1169
S1170
S1171
S1173
S1175
S1185
T1200
S1211
S1243
T1246
T1257
S1259
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation CCRCC S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation COAD S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation GBM S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation HNSCC S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation LSCC S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation LUAD S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation OV S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation PDAC S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation UCEC S13 T20 S353 S494 S501 S505 S507 S508 S510 S870 T1083 S1169 S1170 S1171 S1173 S1175 S1185 T1200 S1211 S1243 T1246 T1257 S1259 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S13
T20
S353
S494
S501
S505
S507
S508
S510
S870
T1083
S1169
S1170
S1171
S1173
S1175
S1185
T1200
S1211
S1243
T1246
T1257
S1259
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S13
T20
S353
S494
S501
S505
S507
S508
S510
S870
T1083
S1169
S1170
S1171
S1173
S1175
S1185
T1200
S1211
S1243
T1246
T1257
S1259
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.