Protein: ENSP00000247226

PLEKHG3:: pleckstrin homology and RhoGEF domain containing G3

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S52	PAKNGAGSLRSRHLP	1	10	-	-	-	-	-	-	-	-	-	-	5	5	-	-	-	-	-	-	-	-
S65	LPNSNNNSSSWLNVK	2	23	-	-	-	-	-	-	-	-	-	-	-	-	-	-	7	1	-	-	6	9
S76	LNVKGPLSPFNSRAA	10	1124	53	-	30	28	71	72	99	-	85	48	98	91	61	56	61	15	105	44	89	18
S423	YPNRYRCSPERLKKA	10	1191	62	-	58	44	91	88	99	-	57	32	103	94	72	65	61	15	100	43	89	18
S432	ERLKKAWSSQDEVST	2	16	-	-	-	-	-	-	-	-	-	-	5	5	-	-	-	-	-	-	6	-
S433	RLKKAWSSQDEVSTN	10	899	33	-	50	45	66	68	73	-	53	30	68	63	41	37	76	18	74	31	66	7
S448	VRQGRRQSEPTKHLL	7	645	6	-	-	-	-	-	90	-	-	-	69	62	78	73	76	17	61	27	68	18
S485	SRSSRRPSGRSPTST	9	866	66	-	31	30	87	84	81	-	85	49	50	44	17	17	-	-	87	37	83	18
S488	SRRPSGRSPTSTEKR	10	1110	104	-	47	47	97	100	98	-	64	36	103	82	40	35	35	6	103	43	52	18
S576	TEDLKALSSEEEEEM	9	684	78	-	99	76	7	2	63	-	63	37	29	27	31	29	-	-	89	38	12	4

Showing 1 to 10 of 68 rows

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S52	PAKNGAGSLRSRHLP	-	-	-	-	-	-	-	-	-	-	-
S65	LPNSNNNSSSWLNVK	-	-	-	-	-	-	-	-	-	-	-
S76	LNVKGPLSPFNSRAA	6.9e-20	-	3.1e-7	0.041	-	1.9e-4	1.6e-15	-9.0e-5	1.2e-5	4.9e-10	0.79
S423	YPNRYRCSPERLKKA	2.9e-24	-	-1.8e-6	6.2e-23	-	9e-10	2.8e-28	5.9e-11	1.5e-4	-1.1e-4	0.96
S432	ERLKKAWSSQDEVST	-	-	-	-	-	-	-	-	-	-	-
S433	RLKKAWSSQDEVSTN	0.027	-	-0.011	-1.9e-6	-	3.3e-6	1.1e-5	0.74	-0.076	2.7e-8	-
S448	VRQGRRQSEPTKHLL	-0.03	-	-	-	-	-	0.52	0.88	2.5e-4	-4.6e-3	-9.8e-11
S485	SRSSRRPSGRSPTST	0.027	-	3.7e-3	-0.18	-	2.3e-6	3.5e-5	-	-	-7.7e-4	-0.1
S488	SRRPSGRSPTSTEKR	2.9e-5	-	-0.29	4.5e-7	-	1e-8	6.8e-22	-6.6e-3	-	-3.7e-10	0.47
S576	TEDLKALSSEEEEEM	-1.3e-9	-	-2.3e-18	-	-	-8.9e-5	0.016	-0.33	-	-0.019	-

Showing 1 to 10 of 68 rows

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000247226Gene: PLEKHG3

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000247226
Gene: PLEKHG3