TRAF2: TNF receptor associated factor 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ca4 chain A
1ca4 chain B
1ca4 chain C
1ca4 chain D
1ca4 chain E
1ca4 chain F
1ca9 chain A
1ca9 chain B
1ca9 chain C
1ca9 chain D
1ca9 chain E
1ca9 chain F
1czy chain A
1czy chain B
1czy chain C
1czz chain A
1czz chain B
1czz chain C
1d00 chain A
1d00 chain B
1d00 chain C
1d00 chain D
1d00 chain E
1d00 chain F
1d00 chain G
1d00 chain H
1d01 chain A
1d01 chain B
1d01 chain C
1d01 chain D
1d01 chain E
1d01 chain F
1d0a chain A
1d0a chain B
1d0a chain C
1d0a chain D
1d0a chain E
1d0a chain F
1d0j chain A
1d0j chain B
1d0j chain C
1d0j chain D
1d0j chain E
1d0j chain F
1f3v chain B
1qsc chain A
1qsc chain B
1qsc chain C
3knv chain A
3m06 chain A
3m06 chain B
3m06 chain C
3m06 chain D
3m06 chain E
3m06 chain F
3m0a chain A
3m0a chain B
3m0a chain C
3m0d chain A
3m0d chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S35 LEAKYLCS ACRNVLR 1 6 - - - - - - - - - - - - - - - - - - 6 - S102 AARREVES LPAVCPS 8 461 62 - 16 13 - - 9 - 7 3 34 33 93 82 - - 3 2 95 9 S109 SLPAVCPS DGCTWKG 3 25 - - 4 4 - - - - - - - - 5 4 - - - - 5 3 S123 GTLKEYES CHEGRCP 6 208 6 - 4 4 - - - - - - 20 16 61 45 14 2 - - 30 6 S160 EHECPERS LSCRHCR 4 86 9 - - - - - - - - - 9 9 26 24 - - 7 2 - - S162 ECPERSLS CRHCRAP 2 18 - - - - - - - - - - 5 4 5 4 - - - - - - S262 KPLLGDQS HAGSELL 1 9 - - - - - - - - - - - - 5 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S35 LEAKYLCS ACRNVLR - - - - - - - - - - - S102 AARREVES LPAVCPS 1.7e-19 - - - - - 2.5e-6 7.5e-16 - - - S109 SLPAVCPS DGCTWKG - - - - - - - - - - - S123 GTLKEYES CHEGRCP 2.4e-11 - - - - - 2.5e-4 7.3e-9 - - - S160 EHECPERS LSCRHCR 2.3e-7 - - - - - - 2.3e-7 - - - S162 ECPERSLS CRHCRAP - - - - - - - - - - - S262 KPLLGDQS HAGSELL - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S35
S102
S109
S123
S160
S162
S262
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation CCRCC S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation COAD S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation GBM S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation HNSCC S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation LSCC S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation LUAD S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation OV S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation PDAC S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation UCEC S35 S102 S109 S123 S160 S162 S262 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S35
S102
S109
S123
S160
S162
S262
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S35
S102
S109
S123
S160
S162
S262
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.